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羊膜和羊膜细胞:对抗组织炎症和纤维化的潜在治疗工具?

Amniotic membrane and amniotic cells: potential therapeutic tools to combat tissue inflammation and fibrosis?

机构信息

Monash Institute of Medical Research, Monash University, Clayton, Victoria 3168, Australia.

出版信息

Placenta. 2011 Oct;32 Suppl 4:S320-5. doi: 10.1016/j.placenta.2011.04.010. Epub 2011 May 12.

Abstract

In addition to the placenta, umbilical cord and amniotic fluid, the amniotic membrane is emerging as an immensely valuable and easily accessible source of stem and progenitor cells. This concise review will focus on the stem/progenitor cell properties of human amniotic epithelial and mesenchymal stromal cells and evaluate the effects exerted by these cells and the amniotic membrane on tissue inflammation and fibrosis.

摘要

除了胎盘、脐带和羊水,羊膜正成为一种极具价值且易于获取的干细胞和祖细胞来源。这篇简明综述将重点关注人羊膜上皮细胞和间充质基质细胞的干细胞/祖细胞特性,并评估这些细胞和羊膜对组织炎症和纤维化的影响。

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