Institute of the Human Brain of Russian Academy of Sciences, 12 a, ul. Academica Pavlova, St. Petersburg 197376, Russia.
Neuroimage. 2011 Jul 15;57(2):565-75. doi: 10.1016/j.neuroimage.2011.04.060. Epub 2011 May 3.
The anterior N2 and P3 waves of event related potentials (ERPs) in the GO/NOGO paradigm in trials related to preparatory set violations in previous studies were inconsistently associated either with action inhibition or conflict monitoring operations. In the present study a paired stimulus GO/NOGO design was used in order to experimentally control the preparatory sets. Three variants of the same stimulus task manipulated sensory mismatch, action inhibition and conflict monitoring operations by varying stimulus-response associations. The anterior N2 and P3 waves were decomposed into components by means of independent component analysis (ICA). The ICA was performed on collection of 114 individual ERPs in the three experimental conditions. Three of the independent components were selectively affected by the task manipulations indicating association of these components with sensory mismatch, action inhibition and conflict monitoring operations. According to sLORETA the sensory mismatch component was generated in the left and right temporal areas, the action suppression component was generated in the supplementary motor cortex, and the conflict monitoring component was generated in the anterior cingulate cortex.
在先前研究中，与预备集违反相关的 GO/NOGO 范式中的事件相关电位（ERP）的前 N2 和 P3 波与动作抑制或冲突监测操作不一致地相关联。在本研究中，使用了成对刺激 GO/NOGO 设计来通过改变刺激-反应关联来实验控制预备集。相同刺激任务的三个变体通过改变刺激-反应关联来操纵感觉失配、动作抑制和冲突监测操作。通过独立成分分析（ICA）将前 N2 和 P3 波分解成成分。ICA 在三个实验条件下的 114 个个体 ERP 集合上进行。三个独立成分被任务操作选择性地影响，表明这些成分与感觉失配、动作抑制和冲突监测操作的关联。根据 sLORETA，感觉失配成分在左右颞区产生，动作抑制成分在补充运动皮层产生，冲突监测成分在前扣带皮层产生。
