子宫混合性苗勒管肿瘤——预后因素：147例临床与组织病理学研究

Mixed müllerian tumours of the uterus--prognostic factors: a clinical and histopathologic study of 147 cases.

作者信息

Larson B, Silfverswärd C, Nilsson B, Pettersson F

机构信息

Department of Obstetrics and Gynaecology, Radiumhemmet, Karolinska Hospital, Stockholm, Sweden.

出版信息

Radiother Oncol. 1990 Feb;17(2):123-32. doi: 10.1016/0167-8140(90)90100-b.

DOI:10.1016/0167-8140(90)90100-b

PMID:2157241

Abstract

One hundred and forty-seven women with uterine mixed Müllerian tumours (UMMT) treated at Radiumhemmet from 1936 through 1981 were reviewed. The prognostic value of clinical and histopathologic data was analysed with bivariate and multivariate techniques. Stage, age and abdominal pain were found to be significant predictors of survival. Surgery and combined radiotherapy (intracavitary + external irradiation) gave in stage I, a lower local failure rate (p = 0.006) and better overall survival (p = 0.001) than surgery in combination with either intracavitary or external irradiation.

摘要

对1936年至1981年在镭疗医院接受治疗的147例子宫混合性苗勒管肿瘤（UMMT）患者进行了回顾性研究。采用双变量和多变量技术分析了临床和组织病理学数据的预后价值。发现分期、年龄和腹痛是生存的重要预测因素。与单纯腔内放疗或体外放疗联合手术相比，I期患者采用手术联合放疗（腔内放疗+体外放疗）局部失败率更低（p = 0.006），总生存率更高（p = 0.001）。