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抗结核治疗的矛盾反应。

Paradoxical response to anti-tubercular treatment.

机构信息

Department of Pediatrics, Lokmanya Tilak Municipal General Hospital and Medical College, Sion, Mumbai 400022, India.

出版信息

Indian J Pharmacol. 2011 Apr;43(2):212-3. doi: 10.4103/0253-7613.77377.

DOI:10.4103/0253-7613.77377
PMID:21572663
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3081467/
Abstract

We report a 5-year-old boy who developed optic neuritis as a paradoxical reaction to anti-tuberculous therapy. Steroids were re-started in the patient with gradual recovery of his vision. The case emphasizes the importance of recognizing paradoxical reactions in patients on anti-tuberculous therapy. Prompt recognition and treatment of such reactions will reduce the associated morbidity.

摘要

我们报告了一例 5 岁男孩,他在抗结核治疗中出现视神经炎,这是一种矛盾反应。在患者中重新开始使用类固醇,其视力逐渐恢复。该病例强调了在接受抗结核治疗的患者中识别矛盾反应的重要性。及时识别和治疗此类反应将降低相关发病率。

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Paradoxical response to anti-tubercular treatment.抗结核治疗的矛盾反应。
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本文引用的文献

1
Bilateral optic neuritis due to isoniazid (INH).异烟肼(INH)引起的双侧视神经炎。
Indian Pediatr. 2010 Jun;47(6):533-5. doi: 10.1007/s13312-010-0083-5.
2
Paradoxical reaction in tubercular meningitis resulting in involvement of optic radiation.结核性脑膜炎中的反常反应导致视辐射受累。
Indian J Ophthalmol. 2009 Mar-Apr;57(2):139-41. doi: 10.4103/0301-4738.45504.
3
BLINDNESS DURING STREPTOMYCIN AND CHLORAMPHENICOL THERAPY.链霉素和氯霉素治疗期间的失明
Br J Ophthalmol. 1961 Aug;45(8):555-9. doi: 10.1136/bjo.45.8.555.
4
Paradoxical response in patients with CNS tuberculosis.中枢神经系统结核患者的反常反应。
J Assoc Physicians India. 2003 Mar;51:257-60.
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Intracranial tuberculoma manifesting during treatment.治疗期间出现的颅内结核瘤。
Indian Pediatr. 1996 Mar;33(3):231-3.
6
Symptomatic intracranial tuberculoma developing during treatment of tuberculosis: a report of 10 patients and review of the literature.
Q J Med. 1987 May;63(241):449-60.