广泛耐药性肺结核病例中的药物性视神经病变
Drug-induced optic neuropathy in a case of extensively drug-resistant pulmonary tuberculosis.
作者信息
Rana Proteesh, Roy Vandana, Ahmad Jamshed
机构信息
Dr Ram Manohar Lohia Hospital and Post Graduate Institute of Medical Education and Research, Department of Pharmacology, New Delhi, India.
Maulana Azad Medical College, Department of Pharmacology, New Delhi, India.
出版信息
J Basic Clin Physiol Pharmacol. 2018 Dec 19;30(1):139-140. doi: 10.1515/jbcpp-2018-0007.
We report a 26-year-old male patient diagnosed with extensively drug-resistant pulmonary tuberculosis presenting with reversible bilateral toxic optic neuropathy induced by the use of linezolid along with high-dose isoniazid. The case emphasizes the importance of recognizing toxic optic neuritis in patients on antitubercular therapy. Prompt recognition and treatment of such adverse drug reactions will reduce the associated morbidity.
我们报告了一名26岁男性患者，被诊断为广泛耐药性肺结核，因使用利奈唑胺和高剂量异烟肼而出现可逆性双侧中毒性视神经病变。该病例强调了在接受抗结核治疗的患者中识别中毒性视神经炎的重要性。及时识别和治疗此类药物不良反应将降低相关的发病率。
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