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一名26岁初产妇合并动脉导管未闭(PDA)伴心力衰竭的病例报告。

Case report of a 26 year old primigravida with patent ductus arteriosus (PDA) in heart failure.

作者信息

Akintunde A A, Opadijo O G

机构信息

Division of Cardiology, LAUTECH Teaching Hospital, Osogbo, Osun State Nigeria.

出版信息

Afr Health Sci. 2011 Mar;11(1):138-40.

Abstract

Congenital heart disease is an important cause of maternal morbidity and mortality during pregnancy. Pregnancy alters the circulatory and respiratory physiology with attendant deleterious effect on the mother with congenital heart disease and the foetus. Additional insult to the circulatory physiology by other factors coexisting together with congenital heart disease can further reduce the cardiac reserve in pregnancy and precipitate heart failure. These factors include anaemia, thromboembolism, hypertension, multiple pregnancy, strenuous physical activity, extremes of temperature and the normal physiological edema of pregnancy.Patent ductus arteriosus (PDA) can present for the first time in pregnancy. Moderate to large PDA result in significant volume overload, left ventricular dilation and dysfunction. In the woman with a hemodynamically important PDA, pregnancy may precipitate or worsen heart failure. We report a successful pregnancy in a 26 year old primigravida with previously undetected patent ductus arteriosus with preeclampsia who presented in heart failure. This case highlights the importance of intensive careful examination of pregnant patients to identify such conditions.

摘要

先天性心脏病是孕期孕产妇发病和死亡的重要原因。妊娠会改变循环和呼吸生理,对患有先天性心脏病的母亲和胎儿产生有害影响。与先天性心脏病并存的其他因素对循环生理的额外损害,可进一步降低孕期心脏储备并引发心力衰竭。这些因素包括贫血、血栓栓塞、高血压、多胎妊娠、剧烈体力活动、极端温度以及孕期正常的生理性水肿。动脉导管未闭(PDA)可能在孕期首次出现。中重度PDA会导致明显的容量超负荷、左心室扩张和功能障碍。对于患有血流动力学意义重大的PDA的女性,妊娠可能会引发或加重心力衰竭。我们报告了一例26岁初产妇成功妊娠的病例,该产妇患有先前未被发现的动脉导管未闭并伴有先兆子痫,出现了心力衰竭。该病例凸显了对孕妇进行全面仔细检查以识别此类病症的重要性。

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本文引用的文献

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Eisenmenger syndrome in pregnancy.妊娠期艾森曼格综合征
Arq Bras Cardiol. 2008 May;90(5):e39-40. doi: 10.1590/s0066-782x2008000500015.
2
Outcome of pregnancy in women with congenital heart disease: a literature review.先天性心脏病女性的妊娠结局:文献综述
J Am Coll Cardiol. 2007 Jun 19;49(24):2303-11. doi: 10.1016/j.jacc.2007.03.027. Epub 2007 Jun 4.

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