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A rare case of patent ductus arteriosus diagnosed during coronary artery bypass grafting operation in a 73-year-old man.一名73岁男性在冠状动脉搭桥手术中被诊断出动脉导管未闭的罕见病例。
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Postnatal diagnosis of maternal congenital heart disease: missed opportunities.产后诊断母亲先天性心脏病:错失的机会。
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A case of patent ductus arteriosus with congestive heart failure in a 80-year-old man.一例 80 岁男性伴有充血性心力衰竭的动脉导管未闭。
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本文引用的文献

1
Eisenmenger syndrome in pregnancy.妊娠期艾森曼格综合征
Arq Bras Cardiol. 2008 May;90(5):e39-40. doi: 10.1590/s0066-782x2008000500015.
2
Outcome of pregnancy in women with congenital heart disease: a literature review.先天性心脏病女性的妊娠结局:文献综述
J Am Coll Cardiol. 2007 Jun 19;49(24):2303-11. doi: 10.1016/j.jacc.2007.03.027. Epub 2007 Jun 4.
3
The influence of percutaneous closure of patent ductus arteriosus on left ventricular size and function: a prospective study using two- and three-dimensional echocardiography and measurements of serum natriuretic peptides.经皮动脉导管未闭封堵术对左心室大小和功能的影响:一项使用二维和三维超声心动图及血清利钠肽测量的前瞻性研究。
J Am Coll Cardiol. 2006 Mar 7;47(5):1060-6. doi: 10.1016/j.jacc.2005.09.067. Epub 2006 Feb 9.
4
Summary of the NHLBI Working Group on Research on Hypertension During Pregnancy.美国国立心肺血液研究所孕期高血压研究工作组总结
Hypertens Pregnancy. 2003;22(2):109-27. doi: 10.1081/PRG-120016792.
5
A comparison of ibuprofen and indomethacin for closure of patent ductus arteriosus.布洛芬与吲哚美辛用于动脉导管未闭封堵的比较。
N Engl J Med. 2000 Sep 7;343(10):674-81. doi: 10.1056/NEJM200009073431001.
6
The pharmacology of the ductus arteriosus.动脉导管的药理学
Pharmacol Rev. 1998 Mar;50(1):35-58.
7
A large family with patent ductus arteriosus and unusual face.一个患有动脉导管未闭且面容异常的大家庭。
J Med Genet. 1993 Jun;30(6):503-5. doi: 10.1136/jmg.30.6.503.
8
Pregnancy and its outcome in women with and without surgical treatment of congenital heart disease.接受和未接受先天性心脏病手术治疗的女性的妊娠情况及其结局。
Am J Cardiol. 1982 Sep;50(3):641-51. doi: 10.1016/0002-9149(82)90334-4.
9
Landmark article Feb 25, 1939: Surgical ligation of a patent ductus arteriosus. Report of first successful case. By Robert E. Gross and John P. Hubbard.里程碑式文章,1939年2月25日:动脉导管未闭的外科结扎术。首例成功病例报告。作者:罗伯特·E·格罗斯和约翰·P·哈伯德。
JAMA. 1984 Mar 2;251(9):1201-2. doi: 10.1001/jama.251.9.1201.
10
The changes in the circulation after birth. Their importance in congenital heart disease.出生后循环系统的变化。它们在先天性心脏病中的重要性。
Circulation. 1970 Feb;41(2):343-59. doi: 10.1161/01.cir.41.2.343.

一名26岁初产妇合并动脉导管未闭(PDA)伴心力衰竭的病例报告。

Case report of a 26 year old primigravida with patent ductus arteriosus (PDA) in heart failure.

作者信息

Akintunde A A, Opadijo O G

机构信息

Division of Cardiology, LAUTECH Teaching Hospital, Osogbo, Osun State Nigeria.

出版信息

Afr Health Sci. 2011 Mar;11(1):138-40.

PMID:21572870
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3092319/
Abstract

Congenital heart disease is an important cause of maternal morbidity and mortality during pregnancy. Pregnancy alters the circulatory and respiratory physiology with attendant deleterious effect on the mother with congenital heart disease and the foetus. Additional insult to the circulatory physiology by other factors coexisting together with congenital heart disease can further reduce the cardiac reserve in pregnancy and precipitate heart failure. These factors include anaemia, thromboembolism, hypertension, multiple pregnancy, strenuous physical activity, extremes of temperature and the normal physiological edema of pregnancy.Patent ductus arteriosus (PDA) can present for the first time in pregnancy. Moderate to large PDA result in significant volume overload, left ventricular dilation and dysfunction. In the woman with a hemodynamically important PDA, pregnancy may precipitate or worsen heart failure. We report a successful pregnancy in a 26 year old primigravida with previously undetected patent ductus arteriosus with preeclampsia who presented in heart failure. This case highlights the importance of intensive careful examination of pregnant patients to identify such conditions.

摘要

先天性心脏病是孕期孕产妇发病和死亡的重要原因。妊娠会改变循环和呼吸生理,对患有先天性心脏病的母亲和胎儿产生有害影响。与先天性心脏病并存的其他因素对循环生理的额外损害,可进一步降低孕期心脏储备并引发心力衰竭。这些因素包括贫血、血栓栓塞、高血压、多胎妊娠、剧烈体力活动、极端温度以及孕期正常的生理性水肿。动脉导管未闭(PDA)可能在孕期首次出现。中重度PDA会导致明显的容量超负荷、左心室扩张和功能障碍。对于患有血流动力学意义重大的PDA的女性,妊娠可能会引发或加重心力衰竭。我们报告了一例26岁初产妇成功妊娠的病例,该产妇患有先前未被发现的动脉导管未闭并伴有先兆子痫,出现了心力衰竭。该病例凸显了对孕妇进行全面仔细检查以识别此类病症的重要性。