Ionita Ciprian N, Hoi Y, Meng H, Rudin S
Department of Physics, Toshiba Stroke Research Center, University at Buffalo (SUNY), 3435 Main Street, Buffalo, NY 14214.
Proc SPIE Int Soc Opt Eng. 2004;5369:295. doi: 10.1117/12.534274.
Asymmetric stents are promising new devices for endovascular treatment of cerebrovascular aneurysms. For in vitro experiment a patch made of stainless steel mesh is directly attached onto a standard stent and deployed so that the patch is placed over the aneurysm orifice. Thus we modify substantially the flow into the aneurysm and decrease the shear stress on the aneurysm walls. We used mesh-patches having different permeabilities and evaluated the flow using Particle Image Velocimetry. PIV provides instantaneous velocity vector measurements in a cross-section of flow containing reflective micro-particles. A pulsed-laser light sheet illuminates the flow in the target area and images are acquired using a CCD camera. By registering the position of the particles in two successive images the fluid velocity vectors components are calculated. From the 2D velocity field a best polynomial fit is made to obtain a smooth function of each velocity with respect to the coordinates. Using the fit, we derived the values of quantities of interest in the plane of acquisition such as: tangent shear stress, vorticity and inflow. We used four meshes of different permeabilities. We found out that by using lower permeability meshes we create better conditions for the embolization of the aneurysm.
不对称支架是用于脑血管动脉瘤血管内治疗的有前景的新型装置。在体外实验中,由不锈钢网制成的补片直接附着在标准支架上并展开,使补片置于动脉瘤口上方。这样我们可大幅改变进入动脉瘤的血流,并降低动脉瘤壁上的剪切应力。我们使用了具有不同渗透率的网片补片,并使用粒子图像测速技术评估血流情况。粒子图像测速技术可在包含反射性微粒的血流横截面中提供瞬时速度矢量测量结果。脉冲激光片照亮目标区域内的血流,并用电荷耦合器件相机采集图像。通过记录两个连续图像中微粒的位置,计算流体速度矢量分量。从二维速度场进行最佳多项式拟合,以获得每个速度相对于坐标的平滑函数。利用该拟合,我们得出采集平面内感兴趣的量的值,如:切向剪切应力、涡度和流入量。我们使用了四种不同渗透率的网片。我们发现,使用较低渗透率的网片可为动脉瘤栓塞创造更好的条件。