Yu S C, Zhao J B
Thermal and Fluids Engineering Division, School of Mechanical and Production Engineering, Nanyang Technological University, Singapore.
Med Eng Phys. 1999 Apr;21(3):133-41. doi: 10.1016/s1350-4533(99)00037-5.
As part of a general investigation on the effects of blood flow patterns in sidewall aneurysm, in vitro steady flow studies on rigid aneurysm models have been conducted using Particle Image Velocimetry over a range of Reynolds number from 200 to 1600. Above Reynolds number 700, one large recirculating vortex would be formed, occupying the entire aneurysmal pouch. The centre of the vortex is located at region near to the distal neck. A pair of counter rotating vortices would however be formed at Reynolds numbers below 700. For all the aneurysm models considered, the vortex strength, in general, is stronger at higher Reynolds numbers but lower at larger aneurysm size. Maximum strength of the vortex is about 15% of the bulk mean velocity in the upstream parent tube. Estimates of the wall shear stresses are derived from the near wall velocity measurements. Highest level of wall shear stresses always appears at the distal neck of the aneurysmal pouch. Stents and springs of different porosity have been used to dampen the flow movement inside the aneurysm so as to induce the possible formation of thrombosis. It is found that the flow movement inside the aneurysmal pouch can be suppressed to less than 5% of the bulk mean velocity by both devices. Furthermore, regions of high wall shear stresses at the distal neck could also be suppressed by almost 90%. The present results would be useful for further improvements in stent (or spring) technology.
作为对侧壁动脉瘤内血流模式影响的一项综合研究的一部分,已使用粒子图像测速技术在200至1600的雷诺数范围内对刚性动脉瘤模型进行了体外稳流研究。雷诺数高于700时,会形成一个大的循环涡,占据整个动脉瘤腔。涡的中心位于靠近远端颈部的区域。然而,在雷诺数低于700时会形成一对反向旋转的涡。对于所有考虑的动脉瘤模型,一般来说,涡强度在较高雷诺数时更强,但在动脉瘤尺寸较大时更低。涡的最大强度约为上游母管中总体平均流速的15%。壁面剪应力的估计值是从近壁速度测量中得出的。壁面剪应力的最高水平总是出现在动脉瘤腔的远端颈部。已使用不同孔隙率的支架和弹簧来抑制动脉瘤内的流动运动,以诱导可能的血栓形成。结果发现,两种装置都能将动脉瘤腔内的流动运动抑制到总体平均流速的5%以下。此外,远端颈部的高壁面剪应力区域也能被抑制近90%。目前的结果将有助于进一步改进支架(或弹簧)技术。