Cervantes Lorenzo J, Mah Francis S
Department of Ophthalmology, Cornea and External Disease, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA.
Clin Ophthalmol. 2011;5:495-502. doi: 10.2147/OPTH.S13778. Epub 2011 Apr 18.
Bacterial conjunctivitis is a common infectious disease of the eye, characterized by conjunctival hyperemia, eyelid edema, and purulent discharge. Although the prevalence and incidence are not well reported, bacterial conjunctivitis represents one of the most frequent causes of patient visits to both primary care physicians and ophthalmologists. Most cases of nongonococcal and nonchlamydial bacterial conjunctivitis are self-limiting and may resolve without intervention. There is a place for treatment, however, which allows for a shorter time to clinical and microbiological resolution which may decrease the mild morbidity, decrease health care costs of visits and potential complications, return patients back to school or the work force, and limit the potential spread of this communicable infection. Gatifloxacin ophthalmic solution is a broad spectrum 8-methoxyfluroroquinolone bactericidal antibiotic, with good activity against Staphylococcus aureus, Streptococcus species, and Gram-negative pathogens. It also has a relatively good resistance profile, making it a more than adequate choice in the treatment of bacterial conjunctivitis when therapy is warranted.
细菌性结膜炎是一种常见的眼部传染病，其特征为结膜充血、眼睑水肿和脓性分泌物。尽管患病率和发病率的报道并不充分，但细菌性结膜炎是患者就诊于初级保健医生和眼科医生的最常见原因之一。大多数非淋菌性和非衣原体性细菌性结膜炎病例是自限性的，可能无需干预即可痊愈。然而，治疗仍有其意义，它可以缩短临床和微生物学治愈时间，可能降低轻微发病率，降低就诊的医疗费用和潜在并发症，使患者重返学校或工作岗位，并限制这种传染病的潜在传播。加替沙星滴眼液是一种广谱8-甲氧基氟喹诺酮类杀菌抗生素，对金黄色葡萄球菌、链球菌属和革兰氏阴性病原体具有良好活性。它还具有相对较好的耐药性，在有必要进行治疗时，是治疗细菌性结膜炎的一个足够好的选择。
