Owens O, Leake R
UNIV GLASGOW,DEPT BIOCHEM,GLASGOW G12 8QQ,SCOTLAND.
Int J Oncol. 1993 Feb;2(2):321-4. doi: 10.3892/ijo.2.2.321.
Epidermal growth factor receptor (EGFR) was assayed and compared in malignant ovaries, benign ovarian tumours and normal ovaries. The EGFR was present in 39.7% of malignant ovaries, 13.3% of benign ovarian tumours and in 15.4% of normal ovaries. In the malignant group 36 samples had a low affinity component, 27 had a high affinity component and 16 had both high and low affinity components. The benign ovarian group had 1 high affinity and 3 low affinity components while the normal ovaries had 3 high affinity and 5 low affinity components. The sensitivity of the EGFR assay was 39.7% and the specificity 85.4%.
对恶性卵巢组织、卵巢良性肿瘤组织和正常卵巢组织中的表皮生长因子受体（EGFR）进行了检测和比较。EGFR在39.7%的恶性卵巢组织、13.3%的卵巢良性肿瘤组织以及15.4%的正常卵巢组织中存在。在恶性组中，36个样本具有低亲和力成分，27个样本具有高亲和力成分，16个样本同时具有高亲和力和低亲和力成分。卵巢良性组有1个高亲和力成分和3个低亲和力成分，而正常卵巢有3个高亲和力成分和5个低亲和力成分。EGFR检测的敏感性为39.7%，特异性为85.4%。
