Owens O, Leake R
UNIV GLASGOW,DEPT BIOCHEM,UNIV AVE,GLASGOW G12 8QQ,SCOTLAND.
Int J Oncol. 1992 Aug;1(3):353-6.
Epidermal growth factor (EGF) and transforming growth factor alpha (TGFalpha) were estimated in extracts of 193 malignant ovarian samples, 42 benign ovarian samples and 71 normal ovaries. TGFalpha was present in 87% of malignant ovaries, 85.7% of benign ovarian tumours and 85.9% of normal ovaries. EGF was present in 30% of malignant ovaries, 35.7% of benign ovarian tumours and 12.7% of normal ovaries. TGFalpha was significantly elevated in both the malignant ovarian and benign ovarian extracts compared to normal ovaries. The median values for EGF was significantly elevated in the benign ovarian group compared to extracts from both malignant and normal ovaries.
在193份恶性卵巢样本、42份良性卵巢样本和71份正常卵巢提取物中对表皮生长因子（EGF）和转化生长因子α（TGFα）进行了评估。TGFα存在于87%的恶性卵巢、85.7%的良性卵巢肿瘤和85.9%的正常卵巢中。EGF存在于30%的恶性卵巢、35.7%的良性卵巢肿瘤和12.7%的正常卵巢中。与正常卵巢相比，恶性卵巢和良性卵巢提取物中的TGFα均显著升高。与恶性和正常卵巢提取物相比，良性卵巢组中EGF的中位数显著升高。
