Turnage R H, Coran A G, Drongowski R A
Section of Pediatric Surgery, University of Michigan Medical School, Ann Arbor.
Ann Surg. 1990 Apr;211(4):463-9. doi: 10.1097/00000658-199004000-00013.
In laboratory models of massive small bowel resection and colectomy, intestinal myotomy has been shown to decrease stool frequency and malabsorption. Using physiologic and anatomic parameters of gastrointestinal function, we assessed the ability of three types of ileal myotomies to improve outcome after total abdominal colectomy, mucosal proctectomy, and endorectal pull-through (ERPT) without an enteric reservoir. Twenty puppies underwent ERPT. These dogs were randomly assigned to three experimental groups or a control group consisting of animals without a myotomy. The myotomies were performed by excising the serosa and muscularis propria of the ileal wall in three different patterns. There was no difference between any of the groups with respect to general health, postoperative weight gain, stool frequency, intestinal transit time, water absorption, electrolyte absorption, barium enemas, neorectal capacity and dimensions, and histology.
在大规模小肠切除和结肠切除的实验室模型中,肠肌切开术已被证明可减少排便频率和吸收不良。利用胃肠功能的生理和解剖参数,我们评估了三种类型的回肠肌切开术在全腹结肠切除、黏膜直肠切除和无肠贮袋的直肠内拖出术(ERPT)后改善预后的能力。20只幼犬接受了ERPT。这些犬被随机分为三个实验组或一个由未行肌切开术的动物组成的对照组。通过以三种不同模式切除回肠壁的浆膜和固有肌层来进行肌切开术。在一般健康状况、术后体重增加、排便频率、肠道转运时间、水分吸收、电解质吸收、钡灌肠、新直肠容量和尺寸以及组织学方面,各实验组之间没有差异。