Coran A G, Sarahan T M, Dent T L, Fiddian-Green R, Wesley J R, Jordan F T
Ann Surg. 1983 Jan;197(1):99-105.
Between June 1977 and November 1981, 26 children and adults with ulcerative colitis have undergone a total colectomy, an endorectal dissection of the rectal mucosa, and an ileoanostomy. A combined abdominoperineal approach was used to perform the operation, and the mucosal-submucosal rectal tube was dissected out intact from the abdominal approach. Every patient survived the operation and showed marked clinical improvement presumably due to resection of the diseased colon. Three patients developed intestinal obstruction that was successfully treated with an enterolysis. A rectal cuff abscess and a retroperitoneal abscess were the only other complications. The postoperative stooling pattern of each patient was obtained through detailed interviews. All the patients were continent during the day and at night one month after surgery. Twenty-two patients had a median stool frequency of seven per 24 hours one month after surgery. At one year, the average number of stools was seven per day. Six patients experienced a stool frequency of seven per 24 hours two years after surgery. The results with this series of patients had encouraged the authors to continue to recommend this approach to children and adults with ulcerative colitis, since it offers an alternative lifestyle that is more attractive to certain patients than the presence of an abdominal stoma.
1977年6月至1981年11月期间,26例溃疡性结肠炎患儿及成人接受了全结肠切除术、直肠黏膜的直肠内剥离术和回肠肛管吻合术。采用联合腹会阴入路进行手术,通过腹部入路完整剥离出黏膜下层直肠管。每位患者均手术成功,且临床症状显著改善,推测这得益于病变结肠的切除。3例患者发生肠梗阻,经肠粘连松解术成功治疗。仅出现了直肠袖带脓肿和腹膜后脓肿这两种其他并发症。通过详细访谈了解每位患者术后的排便模式。术后1个月时,所有患者白天和夜间均能自主控制排便。22例患者术后1个月排便频率中位数为每24小时7次。1年时,平均每日排便次数为7次。6例患者术后2年排便频率为每24小时7次。这一系列患者的治疗结果促使作者继续向溃疡性结肠炎患儿及成人推荐这种手术方法,因为它提供了一种对某些患者比腹部造口更具吸引力的生活方式选择。