Department of Nephrology, Children's Hospital of Zhejiang University School of Medicine, Hangzhou 310003, China.
World J Pediatr. 2011 May;7(2):176-8. doi: 10.1007/s12519-011-0277-5. Epub 2011 May 15.
Follicular bronchiolitis (FB) is an uncommon but important pulmonary manifestation in children.
In this report, we present the clinical presentations and histopathological data of an 8-year-old boy with FB.
The patient had a history of recurrent cough and dyspnea for 5 years with progressive worsening of symptoms. An initial pulmonary function test showed an obstructive ventilatory defect. Chest X-ray demonstrated miliary nodules. High-resolution computed tomography showed reticulonodular opacification and central consolidation. Histopathological examination revealed that lymphoid follicles with reactive germinal centers distributed along the bronchioles. The boy responded favorably to corticosteroid therapy and recovered well.
Diagnosis of FB should be considered when a child presents with chronic bronchial obstruction. Open lung biopsy is necessary for confirmation of the diagnosis.
滤泡性细支气管炎（FB）是儿童中一种不常见但重要的肺部表现。
在本报告中，我们介绍了一例 8 岁男孩 FB 的临床表现和组织病理学数据。
该患者有反复咳嗽和呼吸困难的病史，症状进行性加重，已持续 5 年。最初的肺功能测试显示阻塞性通气功能障碍。胸部 X 线显示粟粒结节。高分辨率计算机断层扫描显示网状结节状混浊和中央实变。组织病理学检查显示淋巴滤泡伴有反应性生发中心，沿细支气管分布。该男孩对皮质类固醇治疗反应良好，恢复良好。
当儿童出现慢性支气管阻塞时，应考虑滤泡性细支气管炎的诊断。开胸肺活检对确诊是必要的。
