Tyshko N V, Zhminchenko V M, Pashorina V A, Seliaskin K E, Saprykin V P, Utembaeva N T, Tutel'ian V A
Vopr Pitan. 2011;80(1):14-28.
The publication presents the results of assessment of impact of genetically modified (GM) maize Liberty Link on prenatal and postnatal development of progeny of 3 generations of Wistar rats. A total of 630 adult animals and 2837 pups were used in the experiment. The animals were divided into 5 groups which got the diets with inclusion of maize: the animals of the experimental group got the diet with the GM-maize, animals of the control group - with near isogenic conventional analogue of the GM-maize, animals of the 1st, 2nd and 3rd reference groups - conventional varieties of maize ROSS 144 MV, ROSS 197 MVW, Dokuchayevskaya 250 MV respectively. The maize was included in the diet at maximum possible level not violating the balance of basic nutrients. Analysis of the data obtained during the study did not reveal any impact of GM-maize on rat progeny development.
该出版物展示了转基因(GM)玉米利比里特对三代Wistar大鼠后代产前和产后发育影响的评估结果。实验共使用了630只成年动物和2837只幼崽。动物被分为5组,给予含玉米的饮食:实验组动物给予含转基因玉米的饮食,对照组动物给予转基因玉米的近等基因常规类似物,第一、第二和第三参考组动物分别给予常规玉米品种ROSS 144 MV、ROSS 197 MVW、Dokuchayevskaya 250 MV。玉米以不违反基本营养素平衡的最大可能水平纳入饮食。对研究期间获得的数据进行分析后,未发现转基因玉米对大鼠后代发育有任何影响。