UMR8638, CNRS-Paris Descartes University, Laboratoire de Chimie Thérapeutique, Faculté des Sciences Pharmaceutiques et Biologiques, 4 av. de l'Observatoire, 75006 Paris, France.
J Org Chem. 2011 Jun 17;76(12):5137-42. doi: 10.1021/jo2001512. Epub 2011 May 24.
Several fluorinated 1,3-diaminocyclopentanes, previously reported to be useful RNA structural probes, can be prepared in a diastereoselective manner from a single bicyclic hydrazine precursor, in 3 to 9 steps.
几种先前被报道为有用的 RNA 结构探针的氟化 1,3-二氨基环戊烷，可以通过单一的双环肼前体以非对映选择性方式在 3 至 9 步反应中制备得到。
