Human Cognitive Neuroscience, University of Edinburgh, Edinburgh, UK.
Arch Clin Neuropsychol. 2011 Jun;26(4):340-8. doi: 10.1093/arclin/acr032. Epub 2011 May 15.
Although several studies have shown that dual-tasking ability is impaired in Alzheimer's disease (AD), the stage at which this deficit manifests remains unclear. This study investigated if a new paper-and-pencil assessment of dual-tasking ability could distinguish between AD, mild cognitive impairment (MCI) and normal ageing in a sample of 50 people with AD, 49 people with MCI, and 50 healthy age-matched controls. The AD group demonstrated a significant impairment in dual-task ability. There was no effect of either MCI or healthy ageing on dual-task performance, indicating that the dual-task impairment is specific to AD.
尽管有几项研究表明，阿尔茨海默病（AD）患者的双重任务能力受损，但这种缺陷表现出来的阶段仍不清楚。本研究调查了在 50 名 AD 患者、49 名 MCI 患者和 50 名健康年龄匹配对照者的样本中，一种新的纸笔式双重任务能力评估是否可以区分 AD、轻度认知障碍（MCI）和正常衰老。AD 组在双重任务能力方面表现出明显的损伤。MCI 或健康衰老对双重任务表现均无影响，表明双重任务损伤是 AD 特异性的。
