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Epigenetic modifications: basic mechanisms and role in cardiovascular disease.

作者信息

Handy Diane E, Castro Rita, Loscalzo Joseph

机构信息

Cardiovascular Division, Department of Medicine, Brigham and Women’s Hospital and Harvard Medical School, Boston, MA, USA.

出版信息

Circulation. 2011 May 17;123(19):2145-56. doi: 10.1161/CIRCULATIONAHA.110.956839.

DOI:10.1161/CIRCULATIONAHA.110.956839
PMID:21576679
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3107542/
Abstract
摘要

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本文引用的文献

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Dynamic link of DNA demethylation, DNA strand breaks and repair in mouse zygotes.DNA 去甲基化、DNA 链断裂与修复在小鼠受精卵中的动态关联
EMBO J. 2010 Jun 2;29(11):1877-88. doi: 10.1038/emboj.2010.80. Epub 2010 May 4.
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Small RNA class transition from siRNA/piRNA to miRNA during pre-implantation mouse development.在小鼠胚胎植入前发育过程中，小 RNA 从 siRNA/piRNA 向 miRNA 的类别转变。
Nucleic Acids Res. 2010 Aug;38(15):5141-51. doi: 10.1093/nar/gkq229. Epub 2010 Apr 12.
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The histone deacetylase Sirt6 regulates glucose homeostasis via Hif1alpha.组蛋白去乙酰化酶 Sirt6 通过 Hif1alpha 调节葡萄糖稳态。
Cell. 2010 Jan 22;140(2):280-93. doi: 10.1016/j.cell.2009.12.041.
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Genome-wide erasure of DNA methylation in mouse primordial germ cells is affected by AID deficiency.在小鼠原始生殖细胞中，基因组范围的 DNA 甲基化消除受 AID 缺乏的影响。
Nature. 2010 Feb 25;463(7284):1101-5. doi: 10.1038/nature08829.
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Differential DNA methylation correlates with differential expression of angiogenic factors in human heart failure.差异 DNA 甲基化与人类心力衰竭中血管生成因子的差异表达相关。
PLoS One. 2010 Jan 13;5(1):e8564. doi: 10.1371/journal.pone.0008564.
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The saving switch.节约开关。
Nat Med. 2010 Jan;16(1):18-21. doi: 10.1038/nm0110-18.
7
Hepatic acyl-coenzyme a:cholesterol acyltransferase-2 expression is decreased in mice with hyperhomocysteinemia.高同型半胱氨酸血症小鼠肝酰基辅酶 A：胆固醇酰基转移酶-2 表达降低。
J Nutr. 2010 Feb;140(2):231-7. doi: 10.3945/jn.109.112920. Epub 2009 Dec 16.
8
Parental origin of sequence variants associated with complex diseases.与复杂疾病相关的序列变异的亲本来源。
Nature. 2009 Dec 17;462(7275):868-74. doi: 10.1038/nature08625.
9
RNA-directed transcriptional gene silencing and activation in human cells.人类细胞中RNA指导的转录基因沉默与激活
Oligonucleotides. 2009 Dec;19(4):299-306. doi: 10.1089/oli.2009.0212.
10
Regulation of the osteoblast-specific transcription factor Osterix by NO66, a Jumonji family histone demethylase.NO66，一种组蛋白去甲基化酶 Jumonji 家族，调控成骨细胞特异性转录因子 Osterix。
EMBO J. 2010 Jan 6;29(1):68-79. doi: 10.1038/emboj.2009.332. Epub 2009 Nov 19.