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饮食因素与胰腺癌风险:一项基于加拿大人群的病例对照研究结果

Dietary factors and risk of pancreatic cancer: results of a Canadian population-based case-control study.

作者信息

Howe G R, Jain M, Miller A B

机构信息

NCIC Epidemiology Unit, University of Toronto, Ontario, Canada.

出版信息

Int J Cancer. 1990 Apr 15;45(4):604-8. doi: 10.1002/ijc.2910450405.

Abstract

Dietary information from a case-control study of pancreatic cancer conducted in Metropolitan Toronto between 1983 and 1986 is reported. A total of 249 cases and 505 population-based controls completed quantitative diet histories from which total caloric intake and the intake of a number of nutrients were estimated. A positive association with total caloric intake was observed with a relative risk of 2.39, 95% confidence interval 1.18-4.83 (highest versus lowest quartile), due primarily to the intake of carbohydrates. Inverse associations were seen with fibre from fruit, vegetable and cereal sources, with a relative of risk of 0.42, 0.22-0.78 (highest versus lowest quartile), for total fibre intake.

摘要

本文报告了1983年至1986年在大多伦多进行的一项胰腺癌病例对照研究的饮食信息。共有249例病例和505名基于人群的对照完成了定量饮食史调查,据此估算了总热量摄入和多种营养素的摄入量。观察到总热量摄入呈正相关,相对风险为2.39,95%置信区间为1.18 - 4.83(最高四分位数与最低四分位数相比),主要归因于碳水化合物的摄入。水果、蔬菜和谷物来源的纤维呈负相关,总纤维摄入量的相对风险为0.42,0.22 - 0.78(最高四分位数与最低四分位数相比)。

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