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3,4,5-三羟基-N'-(1H-吲哚-2-基亚甲基)苯甲酰肼-1H-吲哚-2-甲醛连氮-甲醇(2/1/2)

3,4,5-Trihydr-oxy-N'-(1H-indol-2-ylmethyl-idene)benzohydrazide-1H-indole-2-carbaldehyde azine-methanol (2/1/2).

作者信息

Khaledi Hamid, Alhadi Abeer A, Mohd Ali Hapipah, Robinson Ward T, Abdulla Mahmood A

出版信息

Acta Crystallogr Sect E Struct Rep Online. 2009 Dec 12;66(Pt 1):o105-6. doi: 10.1107/S1600536809052465.

DOI:10.1107/S1600536809052465
PMID:21579996
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2980105/
Abstract

The title compound, 2C(16)H(13)N(3)O(4)·C(18)H(14)N(4)·2CH(4)O, was crystallized from the reaction between 3,4,5-trihydroxy-benzoyl-hydrazine and indole-2-carbaldehyde in a mixture of ethanol and methanol. The compound is a stoichiometric 2:1 cocrystal of the methanol-solvated reaction product, 3,4,5-trihydr-oxy-N'-(1H-indol-2-ylmethyl-idene)benzohydrazide and 1H-indole-2-carbaldehyde azine that arose unexpectedly during the synthesis. The former mol-ecules are linked by O-H⋯O hydrogen bonds and also by π-π stacking inter-actions between benzoyl-hydrazide rings into a two-dimensional network. The methanol solvent mol-ecules are hydrogen bonded to this network. The centrosymmetric azine mol-ecules are not engaged in hydrogen bonding.

摘要

标题化合物2C(16)H(13)N(3)O(4)·C(18)H(14)N(4)·2CH(4)O是由3,4,5-三羟基苯甲酰肼与吲哚-2-甲醛在乙醇和甲醇的混合溶剂中反应结晶得到的。该化合物是甲醇溶剂化反应产物3,4,5-三羟基-N'-(1H-吲哚-2-基亚甲基)苯甲酰肼与1H-吲哚-2-甲醛嗪按化学计量比2:1形成的共晶体，这是在合成过程中意外产生的。前者分子通过O-H⋯O氢键以及苯甲酰肼环之间的π-π堆积相互作用连接成二维网络。甲醇溶剂分子通过氢键与该网络相连。中心对称的嗪分子不参与氢键形成。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3997/2980105/2f000d82090d/e-66-0o105-fig4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3997/2980105/d621f9c85124/e-66-0o105-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3997/2980105/9dccb7a9fab6/e-66-0o105-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3997/2980105/ccc09c03e5f9/e-66-0o105-fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3997/2980105/2f000d82090d/e-66-0o105-fig4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3997/2980105/d621f9c85124/e-66-0o105-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3997/2980105/9dccb7a9fab6/e-66-0o105-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3997/2980105/ccc09c03e5f9/e-66-0o105-fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3997/2980105/2f000d82090d/e-66-0o105-fig4.jpg

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