基于通过最近邻分析获得的二核苷酸频率对寡核苷酸频率进行预测。
Prediction of oligonucleotide frequencies based upon dinucleotide frequencies obtained from the nearest neighbor analysis.
作者信息
Hong J
机构信息
Biochemical Engineering Program, School of Engineering, University of California, Irvine 92717.
出版信息
Nucleic Acids Res. 1990 Mar 25;18(6):1625-8. doi: 10.1093/nar/18.6.1625.
Abstract
A statistical method of predicting hexanucleotide frequencies is presented. The method requires dinucleotide frequencies which can be readily obtained by nearest neighbor analysis. The frequencies of 64 hexanucleotides of E. coli were estimated and compared well with those predicted by a third order Markov chain.
摘要
提出了一种预测六核苷酸频率的统计方法。该方法需要通过最近邻分析很容易获得的二核苷酸频率。估计了大肠杆菌64种六核苷酸的频率，并与三阶马尔可夫链预测的频率进行了很好的比较。
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