原子排列策略设计的 1H 磁共振探针：用于次氯酸盐的多模式检测的双激活探针。
Atom arrangement strategy for designing a turn-on 1H magnetic resonance probe: a dual activatable probe for multimodal detection of hypochlorite.
机构信息
INAMORI Frontier Research Center, Kyushu University, 744 Motooka, Fukuoka 819-0395, Japan.
出版信息
Chem Commun (Camb). 2012 Feb 1;48(10):1565-7. doi: 10.1039/c1cc12044a. Epub 2011 May 17.
PMID:21584328
Abstract
The first dual activatable hypochlorite ((-)OCl)-sensing probe was developed, based on a new proof-of-concept design involving signal-activatable (1)H chemical probes using the triple-resonance NMR technique. The probe enabled fluorescence-(1)H MR dual turn-on detection of (-)OCl in solution and in crude tissue extracts.
摘要
首次开发了一种双重激活的次氯酸根（(-)OCl）感应探针，该探针基于涉及使用三重共振 NMR 技术的信号激活（1）H 化学探针的新概念设计。该探针能够在溶液和粗组织提取物中通过荧光-（1）H MR 双重开启检测 (-)OCl。
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