一种基于香豆素-罗丹明二元体系的用于检测次氯酸的比率型荧光探针。
A ratiometric fluorescent probe for sensing HOCl based on a coumarin-rhodamine dyad.
作者信息
Zhang Yan-Ru, Chen Xin-Peng, Zhang Jia-Yi, Yuan Qiong, Miao Jun-Ying, Zhao Bao-Xiang
机构信息
Institute of Organic Chemistry, School of Chemistry and Chemical Engineering, Shandong University, Jinan 250100, P. R. China.
出版信息
Chem Commun (Camb). 2014 Nov 25;50(91):14241-4. doi: 10.1039/c4cc05976j.
PMID:25283359
Abstract
We developed a ratiometric fluorescent probe for sensing HOCl based on coumarin and rhodamine acid that is directly used as a detection moiety. The probe shows high selectivity and sensitivity toward HOCl under best working conditions of myeloperoxidase by which HOCl can be generated from hydrogen peroxide and chloride.
摘要
我们基于香豆素和罗丹明酸开发了一种用于检测次氯酸（HOCl）的比率型荧光探针，该探针直接用作检测部分。在髓过氧化物酶的最佳工作条件下，该探针对HOCl表现出高选择性和灵敏度，通过髓过氧化物酶可由过氧化氢和氯离子生成HOCl。
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