Alvarez Marlene M, Vieira Ana Carolina R E, Sichieri Rosely, Veiga Gloria V da
Department of Nutrition, Universidade Federal do Rio de Janeiro, Brazil.
Arq Bras Endocrinol Metabol. 2011 Mar;55(2):164-70. doi: 10.1590/S0004-27302011000200009.
To compare the prevalence of metabolic abnormalities (MA) and metabolic syndrome (MS) assessed by different criteria among Brazilian adolescents.
Weighted prevalence of MA and MS were estimated using criteria adapted from the International Diabetes Federation (IDF), National Cholesterol Education Program, Adult Treatment Panel III (NCEP/ATP III), and the World Health Organization (WHO) in a probabilistic sample of 577 students aged 12-19.
The most prevalent MA was low concentration of HDL-C as per IDF (32.5%) and NCEP/ATP III (41.6%) criteria and hypertension as per the WHO's criterion (12.4%). Prevalence of MS using the NCEP/ATP III criterion (6.04%) was five times higher than the WHO's (1.1%) and the IDF's (1.6%) criteria. As expected, MS was significantly higher among overweight than among non-overweight adolescents.
Low prevalence of MS but high prevalence of some MA were found. These findings suggest that the diagnosis of MA is more relevant in clinical practice especially in overweight adolescents.
比较不同标准评估的巴西青少年代谢异常(MA)和代谢综合征(MS)的患病率。
在一个包含577名12 - 19岁学生的概率样本中,采用国际糖尿病联盟(IDF)、美国国家胆固醇教育计划成人治疗小组第三次报告(NCEP/ATP III)和世界卫生组织(WHO)改编的标准估计MA和MS的加权患病率。
根据IDF标准(32.5%)和NCEP/ATP III标准(41.6%),最常见的MA是高密度脂蛋白胆固醇(HDL - C)浓度低;根据WHO标准,最常见的MA是高血压(12.4%)。使用NCEP/ATP III标准的MS患病率(6.04%)比WHO标准(1.1%)和IDF标准(1.6%)高五倍。正如预期的那样,超重青少年中的MS患病率显著高于非超重青少年。
发现MS患病率低,但某些MA患病率高。这些发现表明,MA的诊断在临床实践中更具相关性,尤其是在超重青少年中。