Department of Ophthalmology, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo, 160-8582, Japan.
Minamiaoyama Eye Clinic, Tokyo, Japan.
Jpn J Ophthalmol. 2011 May;55(3):183-189. doi: 10.1007/s10384-011-0026-2. Epub 2011 May 17.
To investigate the age-related alterations in functional visual acuity (FVA) in healthy individuals.
A prospective non-comparative multi-center study.
Fifty-four eyes of 54 normal subjects with best corrected visual acuities better than 20/20 seen at the outpatient clinics of the Department of Ophthalmology at Keio University, Minamiaoyama Eye Clinic and Ishida Eye Clinic were studied.
FVA measurements, Schirmer test, BUT, tear clearance rate and fluorescein vital staining scores were obtained.
Schirmer test scores, BUT values and fluorescein vital staining scores did not show significant changes (p > 0.05), but there were significant differences in tear clearance rates among the age groups (p < 0.05). Tear function index, which is a value obtained from multiplying a Schirmer test score by the tear clearance rate, also showed significant differences in the age groups (p < 0.05). The mean logMAR FVA score decreased significantly in the older groups (p < 0.05), while the mean conventional VA score did not show significant differences among the age groups. Moreover, there were significantly more eyes with lower minimum VA scores in the older age groups (p < 0.05). LogMAR minimum VA appeared to be significantly related to the tear clearance rates in subjects 60 years and older (p < 0.05).
FVA testing seems to be a useful method of assessing the age-related decline in dynamic visual and tear functions.
研究健康个体中功能性视力(FVA)随年龄的变化。
前瞻性非对照多中心研究。
本研究纳入了在庆应义塾大学眼科门诊、Minamiaoyama 眼科诊所和 Ishida 眼科诊所就诊的 54 名最佳矫正视力(BCVA)>20/20 的正常受试者的 54 只眼。
进行了 FVA 测量、Schirmer 试验、泪膜破裂时间(BUT)、泪液清除率和荧光素染色评分。
Schirmer 试验评分、BUT 值和荧光素染色评分无显著变化(p>0.05),但不同年龄组间泪液清除率存在显著差异(p<0.05)。泪液功能指数是 Schirmer 试验评分与泪液清除率的乘积,在不同年龄组间也存在显著差异(p<0.05)。年长组的平均 logMAR FVA 评分显著降低(p<0.05),而常规 VA 评分在不同年龄组间无显著差异。此外,年龄较大组中最低 VA 评分较低的眼数明显更多(p<0.05)。logMAR 最小 VA 似乎与 60 岁及以上受试者的泪液清除率显著相关(p<0.05)。
FVA 测试似乎是评估动态视觉和泪液功能随年龄下降的有用方法。