Hiraoka Takahiro, Miyata Kazunori, Hayashidera Takeshi, Iida Masaharu, Takada Keita, Minami Keiichiro, Oshika Tetsuro
Department of Ophthalmology, Faculty of Medicine, University of Tsukuba, Ibaraki, Japan.
Department of Ophthalmology, Miyata Eye Hospital, Miyazaki, Japan.
PLoS One. 2017 Mar 22;12(3):e0173574. doi: 10.1371/journal.pone.0173574. eCollection 2017.
To investigate the influence of intraocular lens subsurface nanoglistenings (SSNGs) on functional visual acuity (FVA), thirty-nine eyes of 29 patients were examined in this study. The SSNG group comprised 19 eyes of 14 patients (75.7± 5.4 years, mean ± standard deviation), and the control group comprised 20 eyes of 15 patients (73.6 ± 6.5 years). The SSNGs were diagnosed on the basis of the typical whitish IOL appearance upon slit-lamp examination and results of densitometry regarding surface light scattering using Scheimpflug images. The FVA measurement system (AS-28; Kowa, Aichi, Japan) was used to examine changes in continuous visual acuity (VA) over time, and visual function parameters such as FVA, visual maintenance ratio (VMR), maximum VA, minimum VA, standard deviation of VA, and number of blinks were assessed. The results were compared between the SSNG and control groups, and correlations of FVA parameters with the intensity of surface light scattering, time after surgery, and age were also evaluated. There were significant differences in VMR (P = 0.035) and standard deviation of VAs (P = 0.031) between the two groups, although no significant differences were found in baseline VA, FVA, maximum VA, minimum VA, and number of blinks. None of the FVA parameters showed any significant correlations with the intensity of surface light scattering, time after surgery, or age. There is a possibility that VA is unstable during a continuous gazing task in patients with SSNGs.
为研究人工晶状体表面下纳米闪光点（SSNGs）对功能性视力（FVA）的影响，本研究对29例患者的39只眼进行了检查。SSNG组包括14例患者的19只眼（平均年龄75.7±5.4岁，平均值±标准差），对照组包括15例患者的20只眼（平均年龄73.6±6.5岁）。根据裂隙灯检查时人工晶状体典型的发白外观以及使用眼前节分析系统图像进行的表面光散射密度测量结果诊断SSNGs。使用FVA测量系统（AS - 28；日本爱知县柯瓦公司）检查连续视力（VA）随时间的变化，并评估FVA、视力维持率（VMR）、最大VA、最小VA、VA标准差和眨眼次数等视觉功能参数。比较SSNG组和对照组的结果，并评估FVA参数与表面光散射强度、术后时间和年龄的相关性。两组之间的VMR（P = 0.035）和VA标准差（P = 0.031）存在显著差异，尽管在基线VA、FVA、最大VA、最小VA和眨眼次数方面未发现显著差异。FVA参数与表面光散射强度、术后时间或年龄均无显著相关性。SSNGs患者在连续注视任务期间VA有可能不稳定。
