Department of Psychology, University of Leuven, Tiensestraat 102, 3000 Leuven, Belgium.
Clin Rheumatol. 2011 Dec;30(12):1543-8. doi: 10.1007/s10067-011-1772-8. Epub 2011 May 17.
Patients with chronic fatigue syndrome (CFS) often experience depression which may negatively affect prognosis and treatment outcome. Research has shown that depression in CFS is associated with maladaptive or self-critical perfectionism. However, currently, little is known about factors that may explain this relationship, but studies in nonclinical samples suggest that low self-esteem may be an important mediator of this relationship. The present study therefore examined whether self-esteem mediated the cross-sectional association between maladaptive perfectionism and severity of depression in 192 patients meeting Centres for Disease Control and Prevention criteria for CFS. Patients completed self-report measures of maladaptive perfectionism, self-esteem, depression, and fatigue. Regression analyses and more direct tests of indirect effects (i.e., the Sobel test and bootstrapping) were used to test for mediation. Congruent with expectations, we found that self-esteem fully mediated the relationship between maladaptive perfectionism and depression in CFS. Findings from this study suggest that self-esteem may explain the link between maladaptive perfectionism and depression in CFS, which may have important implications for the treatment and prevention of depression in these patients.
慢性疲劳综合征 (CFS) 患者常伴有抑郁，这可能对预后和治疗效果产生负面影响。研究表明，CFS 中的抑郁与适应不良或自我批判的完美主义有关。然而，目前尚不清楚哪些因素可以解释这种关系，但非临床样本的研究表明，低自尊可能是这种关系的重要中介因素。因此，本研究旨在检验在满足疾病控制与预防中心 (CDC) 制定的 CFS 标准的 192 名患者中，自尊是否在适应不良的完美主义与抑郁严重程度的横断面关联中起中介作用。患者完成了适应不良的完美主义、自尊、抑郁和疲劳的自我报告测量。回归分析和更直接的间接效应检验（即 Sobel 检验和自举法）用于检验中介作用。与预期一致，我们发现自尊完全中介了 CFS 中适应不良的完美主义和抑郁之间的关系。本研究的结果表明，自尊可能解释了 CFS 中适应不良的完美主义和抑郁之间的联系，这对这些患者的抑郁治疗和预防可能具有重要意义。
