Gollwitzer H, Gerdesmeyer L, Gradinger R, von Eisenhart-Rothe R
Klinik für Orthopädie und Sportorthopädie, Klinikum rechts der Isar, Technische Universität München, Ismaninger Str. 22, 81675 München, Deutschland.
Orthopade. 2011 Jun;40(6):535-42. doi: 10.1007/s00132-011-1763-0.
The present manuscript provides an overview of current evidence-based data and new clinically relevant developments in the field of hip arthroplasty. A multitude of current clinical trials have focussed on tribology with special interest on metal-on-metal implants. Large trials from implant registries have defined specific risk factors for early implant failure and pseudotumors in surface replacement. Furthermore, new ceramic liners and femoral head implants have been investigated in randomized trials. Apart from other very interesting studies, the results of large meta-analyses are now available for laboratory values in periprosthetic infection, antibiotic prophylaxis, regional anesthesia, prevention of thromboembolism, implant fixation, navigation and clinical pathways to prevent complications.
本手稿概述了髋关节置换领域当前基于证据的数据以及新的临床相关进展。众多当前的临床试验聚焦于摩擦学，特别关注金属对金属植入物。来自植入物登记处的大型试验已确定了表面置换中早期植入物失败和假肿瘤的特定风险因素。此外，新型陶瓷衬垫和股骨头植入物已在随机试验中得到研究。除了其他非常有趣的研究外，大型荟萃分析的结果现在可用于假体周围感染、抗生素预防、区域麻醉、血栓栓塞预防、植入物固定、导航以及预防并发症的临床路径等实验室值。
