空间分析方法（SAM）：一种将分子和环境数据相结合以识别选择候选基因座的软件工具。

Spatial analysis method (sam): a software tool combining molecular and environmental data to identify candidate loci for selection.

机构信息

Istituto di Zootecnica, Università Cattolica del S.Cuore, via E. Parmense 84, 29100 Piacenza, Italy, MicroGIS Foundation for Spatial Analysis (MFSA), La Frasse, 1618 Châtel-Saint-Denis, Switzerland, Laboratoire de Systèmes d'Information Géographique, Ecole Polytechnique Fédérale de Lausanne (EPFL), Bâtiment GC, Station 18, 1015 Lausanne, Switzerland, Laboratoire d'Ecologie Alpine, CNRS-UMR 5553, Université Joseph Fourier, BP 53, 38041 Grenoble cedex 09, France.

出版信息

Mol Ecol Resour. 2008 Sep;8(5):957-60. doi: 10.1111/j.1755-0998.2008.02162.x. Epub 2008 Jun 28.

DOI:10.1111/j.1755-0998.2008.02162.x

PMID:21585940

Abstract

sam is a Windows program designed to detect candidate loci for selection in whole-genome scans. It also gives valuable clues as regards the ecological factors at stake in the selection process. The method used is based on multiple univariate logistic regression models to test for association between allelic frequencies at marker loci and environmental variables. The software reads matrices constituted of presence/absence of molecular markers, and of the corresponding environmental parameters at sampling locations. It provides dynamic analysis tables to process the results. The tool is freely available for download at http://www.econogene.eu/software/sam/.

摘要

山姆是一个 Windows 程序，旨在检测全基因组扫描中选择的候选基因座。它还为选择过程中涉及的生态因素提供了有价值的线索。所使用的方法基于多个单变量逻辑回归模型，以测试标记基因座的等位基因频率与环境变量之间的关联。该软件读取由分子标记的存在/缺失和采样位置的相应环境参数构成的矩阵。它提供动态分析表来处理结果。该工具可在 http://www.econogene.eu/software/sam/ 免费下载。