Hutchinson J C, Friedberg S A
Laryngoscope. 1978 Dec;88(12):1950-5. doi: 10.1288/00005537-197812000-00009.
Fibrous histiocytomas are soft tissue tumors of histiocytic origin. One percent prove to be malignant. Reliable histologic criteria of malignancy are few, if any, and the diagnosis of malignancy often must be made on clinical (metastases) rather than histologic grounds. Thirty-five cases originating in various deep structures of the head and neck, excluding the orbit, have been reported in the literature since 1972. One additional case, a malignant tumor of the submandibular gland, is added herewith. Recurrence following initial surgery has been common and stems from inadequate excision of the primary lesion. Microscopic spread of this tumor from its primary site calls for radical rather than conservative surgical excision. At present, radiotherapy and chemotherapy appear to be of little value in the treatment of these tumors.
纤维组织细胞瘤是起源于组织细胞的软组织肿瘤。其中1%被证明是恶性的。可靠的恶性组织学标准很少（如果有的话），恶性诊断往往必须基于临床（转移情况）而非组织学依据。自1972年以来，文献报道了35例起源于头颈部各种深部结构（不包括眼眶）的病例。本文补充另外1例，即1例下颌下腺恶性肿瘤。初次手术后复发很常见，原因是原发灶切除不充分。这种肿瘤从原发部位的显微镜下扩散需要进行根治性而非保守性手术切除。目前，放疗和化疗在这些肿瘤的治疗中似乎价值不大。
