Department of Psychology, Queen's University, Kingston, Ontario, Canada.
Arch Clin Neuropsychol. 2011 Aug;26(5):385-95. doi: 10.1093/arclin/acr033. Epub 2011 May 17.
The purpose of this study was to examine the possible additive neurocognitive deficits in adults with both attention-deficit/hyperactivity disorder (ADHD) and serious depressive symptoms. Participants were 54 university students who completed a psycho-educational assessment. Three groups were examined: a group with comorbid ADHD and elevated depressive symptoms (ADHD + DEP; N = 18); a group with ADHD only (N = 18); and a group with elevated depressive symptoms only (DEP; N = 18). Group differences were examined on a battery of neurocognitive tests. The ADHD + DEP group performed significantly worse than the other groups on processing speed tasks and delayed recall of conceptual verbal information and significantly worse than the ADHD group on shifting tasks. Depressive symptom severity was significantly correlated with processing speed, verbal memory performance, and shifting in the ADHD and ADHD + DEP groups. Results suggest that the co-occurrence of ADHD and depressive symptoms in adults is associated with additional neurocognitive impairment.
本研究旨在探讨同时患有注意力缺陷/多动障碍(ADHD)和严重抑郁症状的成年人是否存在潜在的认知神经损伤。参与者为 54 名完成心理教育评估的大学生。研究考察了三组人群:一组是共患 ADHD 和抑郁症状升高的人群(ADHD+DEP;N=18);一组是仅患 ADHD 的人群(N=18);一组是仅抑郁症状升高的人群(DEP;N=18)。在一系列神经认知测试中,对组间差异进行了检查。与其他组相比,ADHD+DEP 组在处理速度任务和概念性言语信息的延迟回忆方面表现明显更差,与 ADHD 组相比,在转换任务方面表现明显更差。ADHD 和 ADHD+DEP 组中,抑郁症状严重程度与处理速度、言语记忆表现和转换呈显著相关。结果表明,成年人中 ADHD 和抑郁症状的共病与额外的认知神经损伤有关。