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[分泌性抗体在腺病毒感染中的作用]

[The role of secretory antibodies in adenovirus infection].

作者信息

Rumel' N B, Osidak L V, Radchenko N A, Mil'kint K K, Kalinova E A, Chepik E B

出版信息

Zh Mikrobiol Epidemiol Immunobiol. 1990 Jan(1):68-71.

PMID:2158705
Abstract

The protective role of secretory antibodies in the development of adenovirus infection has been established. More severe and prolonged course of adenovirus infection, accompanied by the involvement of the lower respiratory tract in the process, has been noted in patients with low titers of antibodies, or their absence, in secretions (O to 1:4). The presence of secretory antibodies in a titer of 1:8 considerably alleviated the course of the disease. The antibody titer 1:16 (according to the data of the passive hemagglutination test) has proved to be protective for children and adults in adenovirus infection. The results of the determination of antibodies in the secretions of the upper respiratory tract in the passive hemagglutination test may be used for the purposes of prognostication.

摘要

分泌性抗体在腺病毒感染发展过程中的保护作用已得到证实。在分泌物中抗体滴度低或缺乏(0至1:4)的患者中,已观察到腺病毒感染病程更严重、持续时间更长,且下呼吸道也会参与到这一过程中。滴度为1:8的分泌性抗体的存在可显著减轻疾病病程。抗体滴度1:16(根据被动血凝试验的数据)已被证明对儿童和成人的腺病毒感染具有保护作用。被动血凝试验中对上呼吸道分泌物中抗体的测定结果可用于预后判断。

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