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（E）-N'-（4-硝基-亚苄基）-4-（8-喹啉氧基）丁酰肼

(E)-N'-(4-Nitro-benzyl-idene)-4-(8-quinol-yloxy)butano-hydrazide.

作者信息

Xiahou Guo-Lun, Ding Ye-Chun, Fan Xiao-Na

机构信息

Key Lab of Natural Medicine Research and Development in Jiangxi, Gannan Medical University, Ganzhou, Jiangxi 341000, People's Republic of China.

出版信息

Acta Crystallogr Sect E Struct Rep Online. 2010 Jun 5;66(Pt 7):o1522. doi: 10.1107/S1600536810020039.

DOI:10.1107/S1600536810020039
PMID:21587772
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3007085/
Abstract

In the title compound, C(20)H(18)N(4)O(4), conformation along the bond sequence linking the benzene and quinoline rings, which have a mean inter-planar dihedral angle of 2.7 (5)°, is trans-(+)gauche-trans-trans-(-)gauche-trans-trans. In the crystal structure, a pair of inter-molecular N-H⋯O hydrogen bonds links the mol-ecules into centrosymmetric cyclic R(2) (2)(8) dimers, which are aggregated via π-π inter-actions into parallel sheets [quinoline-benzene ring centroid separation = 3.6173 (16)-3.6511 (16) Å]. The sheets are further connected through weak C-H⋯O inter-actions, giving a supra-molecular two-dimensional network.

摘要

在标题化合物C(20)H(18)N(4)O(4)中，连接苯环和喹啉环的键序列的构象为反式-(+)-gauche-反式-反式-(-)-gauche-反式-反式，苯环和喹啉环的平均平面间二面角为2.7 (5)°。在晶体结构中，一对分子间N-H⋯O氢键将分子连接成中心对称的环状R(2) (2)(8)二聚体，这些二聚体通过π-π相互作用聚集形成平行片层[喹啉-苯环质心间距 = 3.6173 (16)-3.6511 (16) Å]。这些片层通过弱C-H⋯O相互作用进一步连接，形成超分子二维网络。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0c5b/3007085/698a8db385d4/e-66-o1522-fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0c5b/3007085/bdc1cb02ac2d/e-66-o1522-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0c5b/3007085/8800e6e050dc/e-66-o1522-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0c5b/3007085/698a8db385d4/e-66-o1522-fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0c5b/3007085/bdc1cb02ac2d/e-66-o1522-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0c5b/3007085/8800e6e050dc/e-66-o1522-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0c5b/3007085/698a8db385d4/e-66-o1522-fig3.jpg

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