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11 - [(E) - 4 - 溴 - 亚苄基] - 8 - (4 - 溴 - 苯基) - 14 - 羟基 - 3,13 - 二氮杂 - 七环 - [13.7.1.1.0.0.0.0]二十四 - 1(22),15,17,19(23),20 - 五烯 - 10 - 酮

11-[(E)-4-Bromo-benzyl-idene]-8-(4-bromo-phen-yl)-14-hy-droxy-3,13-diaza-hepta-cyclo-[13.7.1.1.0.0.0.0]tetra-cosa-1(22),15,17,19(23),20-pentaen-10-one.

作者信息

Kumar Raju Suresh, Osman Hasnah, Ali Mohamed Ashraf, Hemamalini Madhukar, Fun Hoong-Kun

出版信息

Acta Crystallogr Sect E Struct Rep Online. 2010 Oct 23;66(Pt 11):o2926-7. doi: 10.1107/S1600536810042091.

DOI:10.1107/S1600536810042091
PMID:21589100
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3009063/
Abstract

In the title compound, C(35)H(28)Br(2)N(2)O(2), the piperidone ring adopts a chair conformation and the five-membered ring of the pyrrolidine ring adopts an envelope conformation. The naphthalene ring system makes dihedral angles of 37.12 (8) and 50.62 (9)° with the terminal bromo-substituted benzene rings. The dihedral angle between the two bromo-substituted benzene rings is 72.54 (10)°. In the crystal, adjacent mol-ecules are connected by a pair of inter-molecular C-H⋯O hydrogen bonds, forming an inversion dimer. An intra-molecular O-H⋯N hydrogen bond is also present.

摘要

在标题化合物C(35)H(28)Br(2)N(2)O(2)中，哌啶酮环呈椅式构象，吡咯烷环的五元环呈信封式构象。萘环系与末端溴代苯环的二面角分别为37.12 (8)°和50.62 (9)°。两个溴代苯环之间的二面角为72.54 (10)°。在晶体中，相邻分子通过一对分子间C—H⋯O氢键相连，形成一个反演二聚体。分子内还存在O—H⋯N氢键。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/045e/3009063/5276ce91e3bc/e-66-o2926-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/045e/3009063/019b4ce4e112/e-66-o2926-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/045e/3009063/5276ce91e3bc/e-66-o2926-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/045e/3009063/019b4ce4e112/e-66-o2926-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/045e/3009063/5276ce91e3bc/e-66-o2926-fig2.jpg

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