Cardiovascular Division, Department of Medicine, University of Virginia Health System, Charlottesville, Virginia 22908, USA.
Magn Reson Med. 2011 Jun;65(6):1602-10. doi: 10.1002/mrm.22746. Epub 2011 Jan 10.
Although spiral trajectories have multiple attractive features such as their isotropic resolution, acquisition efficiency, and robustness to motion, there has been limited application of these techniques to first-pass perfusion imaging because of potential off-resonance and inconsistent data artifacts. Spiral trajectories may also be less sensitive to dark-rim artifacts that are caused, at least in part, by cardiac motion. By careful consideration of the spiral trajectory readout duration, flip angle strategy, and image reconstruction strategy, spiral artifacts can be abated to create high-quality first-pass myocardial perfusion images with high signal-to-noise ratio. The goal of this article was to design interleaved spiral pulse sequences for first-pass myocardial perfusion imaging and to evaluate them clinically for image quality and the presence of dark-rim, blurring, and dropout artifacts.
虽然螺旋轨迹具有各向同性分辨率、采集效率和对运动的鲁棒性等多种吸引人的特点，但由于潜在的失谐和不一致的数据伪影，这些技术在首次通过灌注成像中的应用有限。螺旋轨迹对暗边伪影的敏感性也可能较低，暗边伪影至少部分是由心脏运动引起的。通过仔细考虑螺旋轨迹读出时间、翻转角策略和图像重建策略，可以减轻螺旋伪影，从而创建具有高信噪比的高质量首次通过心肌灌注图像。本文的目的是为首次通过心肌灌注成像设计交错螺旋脉冲序列，并对其进行临床评估，以评估图像质量以及暗边、模糊和缺失伪影的存在。
