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用于促进细胞浸润的双峰纤维网的单步静电纺丝。

Single-step electrospinning of bimodal fiber meshes for ease of cellular infiltration.

作者信息

Gentsch Rafael, Boysen Bjoern, Lankenau Andreas, Börner Hans G

机构信息

Department of Colloid Chemistry, Max Planck Institute of Colloids and Interfaces, Am Mühlenberg 1, D-14476 Potsdam, Germany.

出版信息

Macromol Rapid Commun. 2010 Jan 4;31(1):59-64. doi: 10.1002/marc.200900431. Epub 2009 Sep 24.

Abstract

Bimodal fiber meshes with fiber diameters differing by one order of magnitude, are electrospun in a simple one-step process, using a standard single syringe electrospin setup. The nano- and microfiber meshes combine the benefits of nanofibers (cell adhesion, proliferation) with those of microfibers (open structure, large pore size) and are therefore interesting as scaffolds for cellular infiltration.

摘要

通过标准的单注射器电纺装置,采用简单的一步法静电纺丝制备出纤维直径相差一个数量级的双峰纤维网。纳米纤维网和微纤维网兼具纳米纤维(细胞黏附、增殖)和微纤维(开放结构、大孔径)的优点,因此作为细胞浸润支架具有吸引力。

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