Hanchaiphiboolkul Suchat, Poungvarin Niphon, Nidhinandana Samart, Suwanwela Nijasri Charnnarong, Puthkhao Pimchanok, Towanabut Somchai, Tantirittisak Tasanee, Suwantamee Jithanorm, Samsen Maiyadhaj
Prasat Neurological Institute, Department of Medical Services, Ministry of Public Health, Bangkok, Thailand.
J Med Assoc Thai. 2011 Apr;94(4):427-36.
To assess stroke prevalence and stroke risk factors in Thailand.
Thai Epidemiologic Stroke (TES) Study is an ongoing, community based cohort study that has been conducted in five geographic regions of Thailand. Baseline health status survey was started in 2004 and enrollment continued until the end of 2006. All participants who were suspicious of being stroke victims were verified. In this analysis, baseline data of 19,997 participants aged 45 to 80 years were identified and analyzed as a cross-sectional analysis.
Three hundred and seventy six subjects were proved to have a stroke thus resulting the crude prevalence of stroke to be 1.88% (95% CI, 1.69 to 2.07). Age standardization to Segi world standard population was 1.81% (95% CI, 1.62 to 1.99). Crude prevalence among adults aged > or = 65 years was 2.70% (95% CI, 2.28 to 3.11). Stroke prevalence differed among five geographic regions of the country (Bangkok 3.34%, Central region 2.41%, Southern 2.29%, Northern 1.46% and Northeastern 1.09%). Using multiple logistic regression analysis, factors associated with higher stroke prevalence were male gender (p < 0.001), occupational class (p < 0.001), geographic region (p < 0.001), hypertension (p < 0.001), diabetes mellitus (p = 0.002) and hypercholesterolemia (p = 0.026).
Stroke prevalence in Thailand from TES study is higher than previous studies, but it is lower than developed countries, probably due to high case fatality rate in Thai population. Geographic variation in stroke prevalence is found more in Bangkok, Central and Southern regions. Longitudinal follow-up of TES cohort study will provide further information on risk factors and incidence of stroke.
评估泰国的中风患病率及中风危险因素。
泰国流行病学中风（TES）研究是一项正在进行的基于社区的队列研究，在泰国的五个地理区域开展。基线健康状况调查于2004年启动，入组工作持续至2006年底。所有疑似中风患者均得到确诊。在此分析中，确定了19997名年龄在45至80岁之间参与者的基线数据，并作为横断面分析进行了分析。
376名受试者被证实患有中风，因此中风的粗患病率为1.88%（95%置信区间，1.69至2.07）。按照Segi世界标准人群进行年龄标准化后为1.81%（95%置信区间，1.62至1.99）。年龄大于或等于65岁成年人的粗患病率为2.70%（95%置信区间，2.28至3.11）。该国五个地理区域的中风患病率存在差异（曼谷为3.34%，中部地区为2.41%，南部为2.29%，北部为1.46%，东北部为1.09%）。采用多因素逻辑回归分析，与中风患病率较高相关的因素有男性（p<0.001）、职业阶层（p<0.001）、地理区域（p<0.001）、高血压（p<0.001）、糖尿病（p = 0.002）和高胆固醇血症（p = 0.026）。
TES研究显示泰国的中风患病率高于以往研究，但低于发达国家，这可能是由于泰国人群的高病死率所致。中风患病率的地理差异在曼谷、中部和南部地区更为明显。对TES队列研究的纵向随访将提供有关中风危险因素和发病率的更多信息。
