Phasom Junjira, Ungcharoen Ratchadaporn, Pusuwan Pakorn, Phoosuwan Nitikorn
Department of Public Health Administration, Faculty of Public Health, Kasetsart University, Sakon Nakhon, Thailand.
Department of Community Health, Faculty of Public Health, Kasetsart University, Sakon Nakhon, Thailand.
Narra J. 2025 Apr;5(1):e2205. doi: 10.52225/narra.v5i1.2205. Epub 2025 Apr 15.
Stroke is a leading cause of mortality and disability-adjusted life years. Its incidence is rising across Asia, with ischemic stroke accounting for approximately 80% of total stroke cases in Thailand. Stroke often leads to long-term disabilities, including impairments in speech, communication, and cognitive function. The aim of this study was to investigate risk factors associated with newly diagnosed ischemic stroke. A matched case-control study was conducted, including 154 newly diagnosed ischemic stroke cases and 183 non-stroke controls, all with type 2 diabetes mellitus (T2DM). Data were collected between February and September 2022 (post-COVID-19 period) using a structured questionnaire covering socio-demographics, lifestyle factors, perceived social support, and self-care management (SCM). Multivariable logistic regression models were used to estimate adjusted odds ratios (aOR) with 95% confidence intervals (CI). The majority of participants were female (60.8%), Buddhist (92.9%), and agriculturists (66.5%), with a mean age of 58.9 (±9.9) years. Factors associated with ischemic stroke included male (aOR: 3.53; 95%CI: 1.73-7.21), Buddhism (aOR: 3.53, 95%CI: 1.11-11.25), sedentary occupation (aOR: 5.78; 95%CI: 2.61-12.81), and T2DM duration >10 years (aOR: 6.19, 95%CI: 3.55-10.80). Protective factors included age >60 years (aOR = 0.55, 95%CI: 0.31-98) and moderate SCM levels (aOR=0.45, 95%CI: 0.26-0.80). This study highlighted that prolonged T2DM and sedentary occupations significantly contributed to ischemic stroke risk. Targeted prevention strategies, including lifestyle modifications and enhanced diabetes self-care management, may help reduce the burden of ischemic stroke.
中风是导致死亡和伤残调整生命年的主要原因。在亚洲，其发病率正在上升，在泰国，缺血性中风约占中风总病例的80%。中风常常导致长期残疾，包括言语、沟通和认知功能受损。本研究的目的是调查新诊断缺血性中风的相关危险因素。开展了一项匹配病例对照研究，纳入154例新诊断的缺血性中风病例和183例非中风对照，所有研究对象均患有2型糖尿病（T2DM）。在2022年2月至9月期间（新冠疫情后时期），使用一份涵盖社会人口统计学、生活方式因素、感知社会支持和自我护理管理（SCM）的结构化问卷收集数据。采用多变量逻辑回归模型来估计调整后的比值比（aOR）及95%置信区间（CI）。大多数参与者为女性（60.8%）、佛教徒（92.9%）和农业从业者（66.5%），平均年龄为58.9（±9.9）岁。与缺血性中风相关的因素包括男性（aOR：3.53；95%CI：1.73 - 7.21）、佛教（aOR：3.53，95%CI：1.11 - 11.25）、久坐职业（aOR：5.78；95%CI：2.61 - 12.81）以及T2DM病程>10年（aOR：6.19，95%CI：3.55 - 10.80）。保护因素包括年龄>60岁（aOR = 0.55，95%CI：0.31 - 98）和中等水平的SCM（aOR = 0.45，95%CI：0.26 - 0.80）。本研究强调，T2DM病程延长和久坐职业显著增加缺血性中风风险。针对性的预防策略，包括生活方式改变和加强糖尿病自我护理管理，可能有助于减轻缺血性中风负担。
