Research Group Microbial Drugs, Helmholtz Centre for Infection Research , Inhoffenstrasse 7, 38124 Braunschweig, Germany.
J Nat Prod. 2011 Jun 24;74(6):1358-63. doi: 10.1021/np1006789. Epub 2011 May 19.
A family of six novel p-hydroxyacetophenone amides, 1-6, was isolated from Cystobacter ferrugineus, strain Cb G35. Their structures were elucidated by ESI-TOF mass spectrometry and NMR spectroscopy. Feeding experiments with labeled [¹³C₉,¹⁵N]-tyrosine and [d₁₀]-leucine identified the biosynthetic precursors of 1.
从 Cystobacter ferrugineus 菌株 Cb G35 中分离到了六种新型的对羟基苯乙酰胺类化合物 1-6。通过 ESI-TOF 质谱和 NMR 光谱学阐明了它们的结构。用标记的 [¹³C₉,¹⁵N]-酪氨酸和 [d₁₀]-亮氨酸进行的饲喂实验鉴定了 1 的生物合成前体。