Olivier A, Gilson B, Lafontaine S, Pautot J X, Bindi P
Service médecine A, centre hospitalier St.-Nicolas, rue d'Anthouard, 55107 Verdun, France.
Rev Med Interne. 2012 May;33(5):e25-7. doi: 10.1016/j.revmed.2011.03.336. Epub 2011 May 17.
Several cases of sarcoidosis with pulmonary, neurological or ophthalmological involvement occurring during a treatment by anti-TNFα have been reported in the literature. We report a 66-year-old man who presented with renal failure and hypercalcaemia, associated with fatigue, shortness of breath and dry cough. He was receiving infliximab since 2004 for psoriatic arthritis. The diagnosis of sarcoidosis was obtained with biopsy sampling of a mediastinal lymph node, and the lung involvement was documented with lung function tests, bronchoalveolar lavage and computed tomographic scan. Laboratory tests were suggestive of interstitial sarcoid nephritis. Disease course was favourable with corticosteroids and discontinuation of infliximab.
