Faculty of Medicine, Istanbul University, Department of Psychiatry, Millet Street, Capa, 34390 Istanbul, Turkey.
Eur Psychiatry. 2012 Aug;27(6):422-5. doi: 10.1016/j.eurpsy.2011.01.014. Epub 2011 May 17.
The aim of this study is to investigate the relationship between work/study status and symptom severity, functionality and quality of life (QoL) in schizophrenia patients.
Two-hundred and ninety-five chronic schizophrenia patients from 11 centres were included in the study. Symptom severity was measured with Positive and Negative Syndrome Scale for schizophrenia. QoL and functionality was assessed with Global Assessment of Functioning Scale, Quality of Life Scale, Personal and Social Performance Scale, Psychosocial Remission in Schizophrenia Scale, Functional Recovery Scale in Schizophrenia, Performance-Based Skills Assessment-Brief Version and Subjective Well-being under Neuroleptics Scales.
Two-third of the participants (n=194) were unemployed. Forty (13.6%) of the participants were involved in full-time work/study, 29 (9.8%) people were involved in part-time work/study, 13 (4.4%) people were engaged in work/study below 50% of the time, but their job was classified as regular and independent. Those who work/study had lower symptoms, better functioning and higher levels of QoL. Also those who work/study full-time displayed better results on these measures than the participants involved in part-time work/study. Age, education, severity of negative symptoms, gender and duration of remission were found to be related to employment status in the logistic regression analysis.
Our findings suggest that work/study status is an important component of functionality.
本研究旨在探讨工作/学习状态与精神分裂症患者症状严重程度、功能和生活质量（QoL）之间的关系。
本研究纳入了来自 11 个中心的 295 名慢性精神分裂症患者。采用阳性和阴性症状量表评估症状严重程度。采用总体功能评估量表、生活质量量表、个人和社会表现量表、精神分裂症心理社会缓解量表、精神分裂症功能恢复量表、基于表现的技能评估-简明版和抗精神病药物下主观幸福感量表评估 QoL 和功能。
三分之二的参与者（n=194）失业。40 名（13.6%）参与者全职工作/学习，29 名（9.8%）人从事兼职工作/学习，13 名（4.4%）人从事低于 50%工作时间的工作/学习，但他们的工作被归类为常规和独立。工作/学习的患者症状较轻、功能较好、生活质量较高。此外，全职工作/学习的患者在这些指标上的表现优于从事兼职工作/学习的患者。在逻辑回归分析中，发现年龄、教育程度、阴性症状严重程度、性别和缓解持续时间与就业状况有关。
我们的研究结果表明，工作/学习状态是功能的一个重要组成部分。
