Durandy Y, Rubatti M, Couturier R
Department of Perfusion and Intensive Care, Institut Hospitalier Jacques Cartier, Massy, France.
Perfusion. 2011 Sep;26(5):441-6. doi: 10.1177/0267659111408755. Epub 2011 May 18.
As a result of improvements in early outcomes, long-term neurologicalal outcomes are becoming a major issue in pediatric cardiac surgery. The mechanisms of brain injury are numerous, but a vast majority of injuries are impervious to therapy and only a few are modifiable. The quality of perfusion during cardiac surgery is a modifiable factor and cerebral monitoring during bypass is the way to assess the quality of intra-operative cerebral perfusion. Near infrared spectroscopy (NIRS), as a diagnostic tool, has gained in popularity within the perfusion community. However, NIRS is becoming the standard of care before its scientific validation. This manuscript relates four clinical cases, demonstrating the limitations of NIRS monitoring during pediatric cardiac surgery as well as uncertainties about the interpretation of the recorded values. The clinical relevance of cerebral oxymetry is needed before the use of NIRS as a decision making tool. Multimodal brain monitoring with NIRS, trans-cranial Doppler and electroencephalogram are currently under way in several pediatric centers. The benefit of this time-consuming and expensive monitoring system has yet to be demonstrated.
由于早期治疗效果的改善,长期神经学预后正成为小儿心脏手术中的一个主要问题。脑损伤的机制众多,但绝大多数损伤无法通过治疗改善,只有少数是可改变的。心脏手术期间的灌注质量是一个可改变的因素,体外循环期间的脑监测是评估术中脑灌注质量的方法。近红外光谱(NIRS)作为一种诊断工具,在灌注领域越来越受欢迎。然而,NIRS在经过科学验证之前正成为护理标准。本文讲述了四个临床病例,展示了小儿心脏手术期间NIRS监测的局限性以及对所记录值解释的不确定性。在将NIRS用作决策工具之前,需要确定脑血氧饱和度测定的临床相关性。目前,几个儿科中心正在进行NIRS、经颅多普勒和脑电图的多模态脑监测。这种耗时且昂贵的监测系统的益处尚未得到证实。