Suppr超能文献

Hyaluronic acid modulates glioma cell proliferation through its interaction with CD44H in vitro.

作者信息

Koochekpour S, Pilkington G

机构信息

INST PSYCHIAT,DEPT NEUROPATHOL,LONDON SE5 8AF,ENGLAND.

出版信息

Oncol Rep. 1996 Jan;3(1):133-5. doi: 10.3892/or.3.1.133.

Abstract

In a recent study we showed that hyaluronic acid (HA) induces cell detachment and promotes migration and invasion of glioma cells in vitro through its interaction with the cell surface molecule CD44H. In this study, the role of HA in proliferation in eight human glioma-derived cell Lines was investigated. We demonstrate that HA exerts a dose dependent proliferative and anti-proliferative effect on glioma cells. This effect was found to be partially counteracted by a CD44H monoclonal antibody, suggesting the involvement of its high affinity receptor, CD44H and other HA receptors in this process.

摘要

相似文献

3
Suppression of CD44 expression decreases migration and invasion of human glioma cells.
Int J Cancer. 1996 Apr 10;66(2):255-60. doi: 10.1002/(SICI)1097-0215(19960410)66:2<255::AID-IJC20>3.0.CO;2-A.

引用本文的文献

1
The scrambled story between hyaluronan and glioblastoma.透明质酸与脑胶质瘤之间混乱的故事。
J Biol Chem. 2021 Jan-Jun;296:100549. doi: 10.1016/j.jbc.2021.100549. Epub 2021 Mar 17.

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验