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与韦格纳肉芽肿病相关的大脑大量出血。

Massive intracerebral hemorrhage associated with Wegener granulomatosis.

机构信息

Department of Nephrology, Ankara Education and Research Hospital, Ankara, Turkey.

出版信息

Rheumatol Int. 2012 Jun;32(6):1813-4. doi: 10.1007/s00296-011-1954-3. Epub 2011 May 19.

Abstract

Wegener granulomatosis (WG) is a necrotizing granulomatous vasculitis that predominantly affects airways and kidneys. But central nervous system involvement (7-11%) is an uncommon. Massive ICH may occur in the course of WG, and this serious condition is related with high risk of mortality. Therefore, the new treatment strategies may be considered in addition to classical practices in serious organ involvement and recurrent attack. Here, we present an adult patient with WG whose disease was complicated by a massive intracerebral hemorrhage (ICH), which subsequently led to death.

摘要

韦格纳肉芽肿(WG)是一种坏死性肉芽肿性血管炎,主要影响气道和肾脏。但中枢神经系统受累(7-11%)并不常见。WG 可发生大量脑实质出血(ICH),这种严重情况与高死亡率相关。因此,在严重器官受累和复发攻击时,除了经典治疗方法外,可能还需要考虑新的治疗策略。在此,我们报告一例成人 WG 患者,其疾病并发大量脑实质出血(ICH),随后导致死亡。

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