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发展中国家迟发性马尾综合征的脊柱减压治疗效果:50 例病例系列研究。

Outcome of spinal decompression in Cauda Equina syndrome presenting late in developing countries: case series of 50 cases.

机构信息

Department of Orthopaedics, Postgraduate Institute of Medical Education and Research, Sector-12, Chandigarh 160012, India.

出版信息

Eur Spine J. 2011 Dec;20(12):2235-9. doi: 10.1007/s00586-011-1840-4. Epub 2011 May 19.

Abstract

The purpose of this study is to find the clinical outcome of decompression of Cauda Equina presenting late in the course of disease. There were 33 males and 17 females with average age of 48 years, ranging from 25 to 85 years. All patients presented to us with a fully developed Cauda Equina syndrome (CES). All of them presented late with mean delay of 12.2 days. Time interval between bladder and bowel dysfunction and admission to hospital varied from 1 to 35 days. The average follow-up was 34.5 months, ranging from 12 to 60 months. There was no statistically significant difference in time of delay in surgery between the recovered and non-recovered group as tested by Student's t test. But there was a statistically significant positive correlation between duration taken for total recovery and delay in surgery. Anal wink as a predictor of bladder and bowel recovery also showed statistical significance, as patients with an absence had a poorer prognosis for bladder recovery. The result of surgery in CES is not as dramatic and fast as seen after routine disc surgery. Some improvement can be expected with decompression even in those patients presenting late and results are not universally poor as previously thought. The treating physicians of such patients should be aware that the recovery in this group of patients can take an exceptionally long time and hence should involve in constant reassurance and rehabilitation of the patient. Presence of anal wink is a very good predictor of bladder and bowel recovery.

摘要

本研究旨在探讨疾病晚期出现马尾神经受压的临床转归。共有 33 名男性和 17 名女性,平均年龄为 48 岁,年龄范围为 25 至 85 岁。所有患者均表现为完全性马尾神经综合征(CES)。所有患者均出现明显的 CES 表现,且平均延迟就诊时间为 12.2 天。膀胱和肠道功能障碍与入院之间的时间间隔从 1 天到 35 天不等。平均随访时间为 34.5 个月,范围为 12 至 60 个月。虽然通过 Student's t 检验,恢复组和未恢复组之间的手术延迟时间没有统计学差异,但手术延迟时间与完全恢复时间之间存在显著的正相关。肛门反射作为膀胱和肠道恢复的预测指标也具有统计学意义,因为没有肛门反射的患者膀胱恢复预后较差。CES 手术后的结果不像常规椎间盘手术后那样显著和迅速。即使是晚期就诊的患者,通过减压也可以获得一定程度的改善,而且结果并不像以前认为的那样普遍较差。治疗此类患者的医生应该意识到,该组患者的恢复可能需要非常长的时间,因此应该不断地对患者进行安抚和康复。肛门反射的存在是膀胱和肠道恢复的良好预测指标。

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