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侵入性尿动力学研究在马尾综合征的诊断及术后恢复中的作用

Role of Invasive Urodynamic Studies in Establishing Cauda Equina Syndrome and Postoperative Recovery.

作者信息

Mallepally Abhinandan Reddy, Mohapatra Bibhudendu, Das Kalidutta

机构信息

Department of Spine Services, Indian Spinal Injuries Centre, Vasant Kunj, New Delhi, India.

出版信息

Global Spine J. 2022 Sep;12(7):1352-1362. doi: 10.1177/2192568220979640. Epub 2020 Dec 17.

Abstract

STUDY DESIGN

Retrospective with prospective follow-up.

OBJECTIVE

Confirming the diagnosis of CES based purely on symptoms and signs is unreliable and usually associated with high false positive rate. A missed diagnosis can permanently disable the patient. Present study aims to determine the relationship between clinical symptoms/ signs (bladder dysfunction) with UDS, subsequently aid in surgical decision making and assessing post-operative recovery.

METHODS

A prospective follow-up of patients with disc herniation and bladder symptoms from January 2018 to July 2020 was done. All patients underwent UDS and grouped into acontractile, hypocontractile and normal bladder. Data regarding PAS, VAC, GTP, timing to surgery and onset of radiculopathy and recovery with correlation to UDS was done preoperatively and post operatively.

RESULTS

107 patients were studied (M-63/F-44). Patients with PAS present still had acontractile (61%) or hypocontractile (39%) detrusor and with VAC present, 57% had acontractile and 43% hypocontractile detrusors. 10 patients with both PAS and VAC present had acontractile detrusor. 82% patients with acute radiculopathy (<2 days) improved when operated <24 hrs while only 47% showed improvement with chronic radiculopathy. The detrusor function recovered in 66.1% when operated <12 hours, 40% in <12-24 hours of presentation.

CONCLUSION

Adjuvant information from UDS in combination with clinicoradiological findings help in accurate diagnosis even in patients with no objective motor and sensory deficits. Quantitative findings on UDS are consistent with postoperative recovery of patient's urination power, representing improvement and can be used as a prognostic factor.

摘要

研究设计

回顾性研究并进行前瞻性随访。

目的

单纯基于症状和体征来确诊马尾神经综合征(CES)是不可靠的,且通常伴有较高的假阳性率。漏诊可能会使患者永久性致残。本研究旨在确定临床症状/体征(膀胱功能障碍)与尿动力学检查(UDS)之间的关系,进而辅助手术决策并评估术后恢复情况。

方法

对2018年1月至2020年7月期间患有椎间盘突出症和膀胱症状的患者进行前瞻性随访。所有患者均接受了尿动力学检查,并被分为逼尿肌无收缩、收缩功能减退和膀胱功能正常三组。术前和术后收集了关于逼尿肌压力(PAS)、腹压(VAC)、逼尿肌-括约肌协同失调(GTP)、手术时机、神经根病发作情况以及与尿动力学检查相关的恢复情况的数据。

结果

共研究了107例患者(男性63例/女性44例)。存在逼尿肌压力的患者中,仍有61%的逼尿肌无收缩或39%的逼尿肌收缩功能减退;存在腹压的患者中,57%的逼尿肌无收缩,43%的逼尿肌收缩功能减退。10例同时存在逼尿肌压力和腹压的患者逼尿肌无收缩。急性神经根病(<2天)患者在发病<24小时内接受手术时,82%的患者病情改善,而慢性神经根病患者只有47%病情改善。在发病<12小时内接受手术的患者中,66.1%的患者逼尿肌功能恢复;在发病12 - 24小时内接受手术的患者中,40%的患者逼尿肌功能恢复。

结论

尿动力学检查的辅助信息与临床放射学检查结果相结合,即使对于没有客观运动和感觉功能障碍的患者也有助于准确诊断。尿动力学检查的定量结果与患者排尿能力的术后恢复情况一致,代表了病情改善,可作为一个预后因素。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/12e0/9394000/753fc69919d7/10.1177_2192568220979640-fig1.jpg

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