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本文引用的文献

1
Wound edge microvascular blood flow during negative-pressure wound therapy: examining the effects of pressures from -10 to -175 mmHg.负压伤口治疗期间伤口边缘微血管血流:研究-10 至-175mmHg 压力的影响。
Plast Reconstr Surg. 2010 Feb;125(2):502-509. doi: 10.1097/PRS.0b013e3181c82e1f.
2
Short periodic applications of the vacuum-assisted closure device cause an extended tissue response in the diabetic mouse model.短期周期性使用真空辅助闭合装置会引起糖尿病小鼠模型的组织反应延长。
Plast Reconstr Surg. 2009 Nov;124(5):1458-1465. doi: 10.1097/PRS.0b013e3181bbc829.
3
V.A.C. Therapy in the management of paediatric wounds: clinical review and experience.负压封闭引流技术在儿童伤口处理中的应用:临床综述与经验
Int Wound J. 2009 Aug;6 Suppl 1(Suppl 1):1-26. doi: 10.1111/j.1742-481X.2009.00607.x.
4
Vacuum-assisted closure therapy increases local interleukin-8 and vascular endothelial growth factor levels in traumatic wounds.负压封闭引流疗法可提高创伤伤口局部白细胞介素-8和血管内皮生长因子水平。
J Trauma. 2009 Mar;66(3):749-57. doi: 10.1097/TA.0b013e318171971a.
5
Cost-effectiveness of negative pressure wound therapy for postsurgical patients in long-term acute care.负压伤口治疗对长期急性护理中术后患者的成本效益
Adv Skin Wound Care. 2009 Mar;22(3):122-7. doi: 10.1097/01.ASW.0000305452.79434.d9.
6
The mechanism of action of the vacuum-assisted closure device.负压封闭引流装置的作用机制。
Plast Reconstr Surg. 2008 Sep;122(3):786-797. doi: 10.1097/PRS.0b013e31818237ac.
7
Negative pressure wound therapy: a systematic review on effectiveness and safety.负压伤口治疗:关于有效性和安全性的系统评价
Eur J Vasc Endovasc Surg. 2008 Oct;36(4):438-48. doi: 10.1016/j.ejvs.2008.06.010. Epub 2008 Aug 3.
8
Disagreement in primary study selection between systematic reviews on negative pressure wound therapy.负压伤口治疗系统评价中在主要研究选择方面存在分歧。
BMC Med Res Methodol. 2008 Jun 26;8:41. doi: 10.1186/1471-2288-8-41.
9
Retrospective clinical evaluation of gauze-based negative pressure wound therapy.基于纱布的负压伤口治疗的回顾性临床评估
Int Wound J. 2008 Jun;5(2):280-6. doi: 10.1111/j.1742-481X.2008.00485.x.
10
Securing skin grafts to microvascular free flaps using the vacuum-assisted closure (VAC) device.使用负压封闭引流(VAC)装置将皮肤移植物固定于游离微血管皮瓣。
Ann Plast Surg. 2007 May;58(5):573-6. doi: 10.1097/01.sap.0000237638.93453.66.

负压伤口疗法:外科重建大面积或复杂皮肤和软组织缺损的辅助治疗方法。

Negative pressure wound therapy: an adjuvant to surgical reconstruction of large or difficult skin and soft tissue defects.

机构信息

Department of Plastic and Reconstructive Surgery, Hanil General Hospital, Seoul, Korea.

出版信息

Int Wound J. 2011 Aug;8(4):406-11. doi: 10.1111/j.1742-481X.2011.00813.x. Epub 2011 May 19.

DOI:10.1111/j.1742-481X.2011.00813.x
PMID:21595830
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7950917/
Abstract

Wide and deep wound defects are a challenge to surgeons, particularly when aggressive or more radical operations are unavailable. This article introduces refined techniques, indications and the clinical experience of the application of negative pressure wound therapy (NPWT) as an easy ancillary wound dressing method for the reconstruction of large or difficult skin and soft tissue defects. The authors used NPWT on 88 patients as an adjuvant therapy before reconstructive surgery since 2006. NPWT was applied for two different treatment strategies: as an adjuvant therapy to facilitate the formation of a healthy wound bed and to reduce the size and depth of a defect. NPWT was used as an alternative dressing method for skin grafting for infants or mobile skin surfaces such as the neck, penis, dorsum of the hand, knee joint, abdomen, etc. There were no typical wound complications. NPWT application, if used appropriately, produces successful surgical reconstructions for large, deep skin and soft tissue defects without extensive or radical flap surgery or loss of skin graft.

摘要

广泛而深的创伤性缺损给外科医生带来了挑战,尤其是在无法进行激进或更彻底的手术时。本文介绍了负压伤口治疗(NPWT)技术的改进、适应证以及在重建大面积或复杂皮肤和软组织缺损中的应用经验。作者自 2006 年以来,将 NPWT 作为重建手术的辅助治疗方法,应用于 88 例患者。NPWT 采用两种不同的治疗策略:作为辅助治疗方法,促进健康的创面床形成,并减少创面的大小和深度;将 NPWT 作为替代敷料,用于婴儿或活动皮肤表面(如颈部、阴茎、手背部、膝关节、腹部等)的植皮。没有出现典型的伤口并发症。如果使用得当,NPWT 可成功地对大面积、深部的皮肤和软组织缺损进行手术重建,而无需进行广泛或彻底的皮瓣手术或植皮丢失。