Dalla Lana School of Public Health, University of Toronto, 155 College Street, Toronto, Ontario, Canada M5T 3M7.
Prev Med. 2011 Sep;53(3):118-20. doi: 10.1016/j.ypmed.2011.05.001. Epub 2011 May 8.
The efficacy of screening by clinical breast examination (CBE) and/or breast self-examination (BSE) is reviewed using indirect evidence from randomized breast screening trials and that from observational studies. In countries where breast cancer is diagnosed at an advanced stage, screening by CBE with the teaching of BSE as an integral component will probably be effective in reducing breast cancer mortality. However, in technically advanced countries where adequate treatment is given, no screening modality is likely to be sufficiently beneficial to outweigh the harms of screening, especially false positives and over-diagnosis.
使用来自随机乳房筛查试验和观察性研究的间接证据，对临床乳房检查（CBE）和/或乳房自我检查（BSE）筛查的效果进行了审查。在乳腺癌诊断处于晚期的国家，将 CBE 筛查与 BSE 的教学作为一个组成部分，可能会有效降低乳腺癌死亡率。然而，在技术先进的国家，给予充分的治疗后，任何筛查方式都不太可能带来足够的益处，超过筛查的危害，特别是假阳性和过度诊断。
