比较上臂和下臂袖带压迫时颈-桡动脉脉搏波速度的充血变化。
Comparison of hyperemic changes in carotid-radial pulse wave velocity by upper and lower arm cuff occlusion.
机构信息
Division of Cardiovascular Medicine, State University of New York Downstate Medical Center, Brooklyn, NY 11203, USA.
出版信息
Angiology. 2011 Jul;62(5):409-14. doi: 10.1177/0003319710389022.
UNLABELLED
Carotid-radial pulse wave velocity (PWV) normally decreases following release of upper arm cuff occlusion (hyperemia). Lower arm (LA) elicits less brachial artery dilation than upper arm (UA) occlusion but more closely reflects endothelial function. Using applanation tonometry, we compared changes (Δ) in PWV induced by UA and LA hyperemia in 65 healthy participants. Pulse wave velocity was measured serially. Both techniques decreased PWV maximally at 1 minute with gradual return to baseline by 9 minutes. ΔPWV(1min) was greater for UA than LA occlusion (-11.5% vs -6.8%, P = .02). Multivariate analysis showed arm location independently related to ΔPWV (P = .036). In participants with variable cardiovascular risk, PWV decline lessened with increasing Framingham risk for both techniques.
IN CONCLUSION
UA and LA occlusion decrease PWV maximally at 1 minute after release of arterial occlusion. PWV(1min) decline are more marked after UA than LA occlusion and progressively lessens with increasing Framingham risk.
未标记
通常情况下，在上臂袖带充气（充血）释放后，颈动脉 - 桡动脉脉搏波速度（PWV）会降低。与肱动脉闭塞相比，小臂（LA）引起的肱动脉扩张程度较小，但更能反映内皮功能。我们使用平板张力法比较了 65 名健康参与者在上臂（UA）和小臂（LA）充血时引起的 PWV 变化（Δ）。连续测量脉搏波速度。两种技术都能使 PWV 在 1 分钟时最大程度地降低，到 9 分钟时逐渐恢复到基线。与 LA 闭塞相比，UA 闭塞时 ΔPWV（1min）更大（-11.5%对-6.8%，P =.02）。多变量分析显示，手臂位置与 ΔPWV 独立相关（P =.036）。在心血管风险不同的参与者中，两种技术的Framingham 风险增加，PWV 下降幅度均减小。
结论
UA 和 LA 闭塞在动脉闭塞释放后 1 分钟内最大程度地降低 PWV。UA 比 LA 闭塞后的 PWV（1min）下降更明显，随着 Framingham 风险的增加，PWV 下降逐渐减少。
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