Center for Systems Biology, Mechanical Engineering and Computer Science, University of Iceland, Reykjavik, Iceland.
Bioinformatics. 2011 Jul 15;27(14):2009-10. doi: 10.1093/bioinformatics/btr308. Epub 2011 May 19.
Genome-scale metabolic networks are widely used in systems biology. However, to date no freely available tool exists that ensures quality control during the reconstruction process.
Here, we present a COBRA toolbox extension, rBioNet, enabling the construction of publication-level biochemical networks while enforcing necessary quality control measures. rBioNet has an intuitive user interface facilitating the reconstruction process for novices and experts.
The rBioNet is freely available from http://opencobra.sourceforge.net.
基因组规模的代谢网络在系统生物学中被广泛应用。然而,到目前为止,还没有免费的工具可以在重建过程中确保质量控制。
在这里,我们展示了一个 COBRA 工具箱扩展 rBioNet,它能够构建发表级别的生化网络,同时执行必要的质量控制措施。rBioNet 具有直观的用户界面,方便新手和专家进行重建过程。
rBioNet 可从 http://opencobra.sourceforge.net 免费获得。